Effects of High Doses of 17[beta]-estradiol and Ovariectomy on 7, 12-Dimethylbenz[a]anthracene-Induced Mammary Carcinomas and Dysplasias in Neonatally Androgenized Female Sprague-Dawley Rats

Inbred, female Sprague-Dawley rats were neonatally androgenized at the age of 2 days by subcutaneous injections of 1.25 mg testosterone propionate and divided into 4 groups. At the age of 50 days, rats of all groups were given 20 mg 7, 12-dimethylbenz[a]anthracene (DMBA). Four weeks after the admini...

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Veröffentlicht in:Journal of toxicologic pathology 2000-04, Vol.13 (2), p.77
Hauptverfasser: Kawaguchi, Hiroaki, Sato, Kenichi, Omachi, Katsumi, Funato, Mamoru, Nagata, Ryoichi, Yoshida, Hiroki
Format: Artikel
Sprache:eng
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