Superior outcome after neoadjuvant chemotherapy with docetaxel, anthracycline, and cyclophosphamide versus docetaxel plus cyclophosphamide: results from the NATT trial in triple negative or HER2 positive breast cancer

The purpose of this study is to evaluate the efficacy and safety of docetaxel plus cyclophosphamide (TC) compared with docetaxel, anthracycline, and cyclophosphamide (TEC) in neoadjuvant treatment of triple negative or HER2 positive breast cancer. Eligible breast cancer patients were randomized to r...

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Veröffentlicht in:	Breast cancer research and treatment 2013-12, Vol.142 (3), p.549-558
Hauptverfasser:	Chen, Xiaosong, Ye, Guolin, Zhang, Chenfang, Li, Xinzheng, Chen, Yiding, Xie, Xiaohong, Zheng, Hong, Cao, Yali, Wu, Kejin, Ni, Duo, Tang, Jinhai, Wei, Ziguo, Shen, Kunwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvant treatment Adult Aged Anthracyclines Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Breast Neoplasms - mortality Breast Neoplasms - pathology Cancer Cancer research Cancer therapies Care and treatment Chemotherapy Clinical Trial Comparative analysis Comparative studies Cyclophosphamide Cyclophosphamide - administration & dosage Cyclophosphamide - adverse effects Cyclophosphamide - therapeutic use Docetaxel Etoposide - adverse effects Etoposide - therapeutic use Female Gynecology. Andrology. Obstetrics Humans Lymphatic Metastasis Mammary gland diseases Medical prognosis Medical sciences Medicine Medicine & Public Health Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoadjuvant Therapy Neoplasm Staging Oncology Patient outcomes Receptor, ErbB-2 - metabolism Taxoids - administration & dosage Taxoids - adverse effects Taxoids - therapeutic use Treatment Outcome Triple Negative Breast Neoplasms - drug therapy Triple Negative Breast Neoplasms - mortality Triple Negative Breast Neoplasms - pathology Tumors
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