Cytogenetic Study of Fragile Sites and Sister Chromatid Intercrossing

Cytogenetic Study of Fragile Sites and Sister Chromatid Intercrossing

Recently it has been suggested that there is a relationship between fragile sites (FS) in chromosomes and “sister chromatid intercrossing” (SCI). We have analyzed such relationship in a family study of the expression of FS and SCI using TC 199 medium. In a 43.64% of the cases, the observed SCI were...

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Veröffentlicht in:CYTOLOGIA 1993/12/25, Vol.58(4), pp.351-354
Hauptverfasser: Arrieta, M. I., Martinez, B., Lobato, N., Criado, B., Nuñez, T., Echarri, A., Lostao, C. M.
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Sprache:eng
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Biological and medical sciences
Cytogenetics
Fundamental and applied biological sciences. Psychology
Genetics of eukaryotes. Biological and molecular evolution
Human
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container_end_page 354
container_issue 4
container_start_page 351
container_title CYTOLOGIA
container_volume 58
creator Arrieta, M. I.
Martinez, B.
Lobato, N.
Criado, B.
Nuñez, T.
Echarri, A.
Lostao, C. M.
description Recently it has been suggested that there is a relationship between fragile sites (FS) in chromosomes and “sister chromatid intercrossing” (SCI). We have analyzed such relationship in a family study of the expression of FS and SCI using TC 199 medium. In a 43.64% of the cases, the observed SCI were located at the same sites of the expressed FS in our sample. The present study supports the suggestion that there could be a relationship between FS and SCI.
doi_str_mv 10.1508/cytologia.58.351
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subjects Biological and medical sciences
Cytogenetics
Fundamental and applied biological sciences. Psychology
Genetics of eukaryotes. Biological and molecular evolution
Human
title Cytogenetic Study of Fragile Sites and Sister Chromatid Intercrossing
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