PEG-mediated Facile Protocol for N-Boc Protection of Amines

PEG-mediated Facile Protocol for N-Boc Protection of Amines

We have reported an efficient and eco-friendly protocol for the protection of various structurally and electronically divergent aryl and aliphatic amines using (Boc)2O in the presence of PEG-400 at room temperature. The reaction gave excellent yields with low as well as high molecular weight PEGs.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemistry letters 2010-11, Vol.39 (11), p.1127-1129
Hauptverfasser: Siddaiah, V, Basha, G. M, Rao, G. Padma, Prasad, U. Viplava, Rao, R. Suryachendra
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We have reported an efficient and eco-friendly protocol for the protection of various structurally and electronically divergent aryl and aliphatic amines using (Boc)2O in the presence of PEG-400 at room temperature. The reaction gave excellent yields with low as well as high molecular weight PEGs.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2010.1127