Synthesis, Spectroscopic and Cytotoxic Studies of Biologically Active New Schiff Bases Derived from p-Nitrobenzaldehyde
Thirteen new Schiff bases derived from p-nitrobenzaldehyde were synthesized by condensation with the appropriate amines. An unusual reduction of the p-nitrobenzaldehyde to the corresponding alcohol was also observed in one of the reactions. The structures of the compounds were identified using spect...
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| Veröffentlicht in: | Chemical & Pharmaceutical Bulletin 2007, Vol.55(7), pp.1070-1072 |
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| container_end_page | 1072 |
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| container_issue | 7 |
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| container_title | Chemical & Pharmaceutical Bulletin |
| container_volume | 55 |
| creator | Iqbal, Amjid Siddiqui, Hamid Latif Ashraf, Chaudhary Muhammad Bukhari, Mujahid Hussain Akram, Chaudhary Muhammad |
| description | Thirteen new Schiff bases derived from p-nitrobenzaldehyde were synthesized by condensation with the appropriate amines. An unusual reduction of the p-nitrobenzaldehyde to the corresponding alcohol was also observed in one of the reactions. The structures of the compounds were identified using spectroscopic techniques. Cytotoxicity for the titled compounds was studied against Brine Shrimp, used as the test animal. |
| doi_str_mv | 10.1248/cpb.55.1070 |
| format | Article |
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An unusual reduction of the p-nitrobenzaldehyde to the corresponding alcohol was also observed in one of the reactions. The structures of the compounds were identified using spectroscopic techniques. 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Pharm. Bull.</addtitle><description>Thirteen new Schiff bases derived from p-nitrobenzaldehyde were synthesized by condensation with the appropriate amines. An unusual reduction of the p-nitrobenzaldehyde to the corresponding alcohol was also observed in one of the reactions. The structures of the compounds were identified using spectroscopic techniques. 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| fulltext | fulltext |
| identifier | ISSN: 0009-2363 |
| ispartof | Chemical and Pharmaceutical Bulletin, 2007, Vol.55(7), pp.1070-1072 |
| issn | 0009-2363 1347-5223 |
| language | eng |
| recordid | cdi_proquest_journals_1460388232 |
| source | MEDLINE; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | Amines - chemistry Animals Artemia - drug effects Benzaldehydes - chemistry biological activity Dose-Response Relationship, Drug Molecular Structure p-nitrobenzadehyde primary amine Schiff Bases - chemical synthesis Schiff Bases - classification Schiff Bases - pharmacology Toxicity Tests unusual aldehyde reduction |
| title | Synthesis, Spectroscopic and Cytotoxic Studies of Biologically Active New Schiff Bases Derived from p-Nitrobenzaldehyde |
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