Synthesis of 1, 4-Dihydropyridine-5-phosphonates and Their Calcium-Antagonistic and Antihypertensive Activities

The effect of the 3-carboxylic-ester variation in 2, 2-dimethyltrimethylene 3-alkoxycarbonyl-4-aryl-1, 4-dihydro-2, 6-dimethyl-5-pyridinephosphonates (1) was investigated with relation to the calcium-antagonistic and antihypertensive activities : the analogs contaning the alkyl groups of not more th...

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1992-09, Vol.40 (9), p.2362
Hauptverfasser: SAKODA, Ryozo, KAMIKAWAJI, Yoshimasa, SETO, Kiyotomo
Format: Artikel
Sprache:eng
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