Isolation and Characterization of Phenolic Compounds from Magnoliae Cortex Produced in China

A chemical examination of Magnoliae Cortex produced in China (Magnolia officinalis REHD. et WIL S., Magnoliaceae) has led to the isolation of eighteen new lignans and related compounds [four monoterpenyl-lignans : piperitylmagnolol (3), dipiperitylmagnolol (4), piperitylhonokiol (5) and bornylmagnolol (6); seven lignans : magnaldehydes B(8), C(9), magnolignans A(10), B(11), C(12), D(13) and E(14); three norlignans : magnatriol B(16), magnaldehydes D(17) and E(18); and four dilignans : magnolignans F(19), G(20), H(21) and I(22)], together with randainal (7), randaiol (15), sinapic aldehyde, syringaresinol, syringaresinol 4'-O-β-D-glucopyranoside and 6'-O-methylhonokiol. Their structures were determined by the chemical and spectral methods.