Macromolecule-Macromolecule Interaction in Drug Distribution

The effect of α-globulin, the dominant binding protein for fractionated 3H-heparin, on the hepatic uptake of 3H-heparin was studied by liver perfusion experiments in rats. Fractionated 3H-heparin concentration in the recirculated perfusate declined one-exponentially with time for each of six initial...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 1990-10, Vol.38 (10), p.2821
Hauptverfasser:	WATANABE, Jun, MURANISHI, Hiroya, NAKAGAKI, Hisashi, YUASA, Hiroaki, OZEKI, Shoji
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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