Synthesis of Active Center-Directed Prptide Inhibitors of Plasmin

Active center-directed peptide inhibitors of plasmin were designed based on the structure of specific substrates of plasmin and synthesized by a conventional solution method. Their effects on plasmin were examined and the structure-activity relationship was studied. D-Ile-Phe-Lys-BZA (4-benzoylanili...

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1988/04/25, Vol.36(4), pp.1289-1297
Hauptverfasser: OKADA, YOSHIO, TSUDA, YUKO, TENO, NAOKI, WANAKA, KEIKO, BOHGAKI, MIYAKO, HIJIKATA-OKUNOMIYA, AKIKO, NAITO, TAKETOSHI, OKAMOTO, SHOSUKE
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Sprache:eng
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