Formation of S-[5-(2'-Deoxyuridyl)] thiol Compounds in the Dehalogenation of 5-Bromo- and 5-Iodo-2'-deoxyuridine with Cysteine Derivatives

Dehalogenations of 5-bromo- and 5-iodo-2'-deoxyuridine by thiol compounds in aqueous solutions were studied. The thiols used were cysteine, cysteine methyl- and ethyl-esters, cysteamine, homocysteine, glutathione, 2-mercaptoethanol, and 2-mercaptopropionic acid. The products of these reactions...

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1978/06/25, Vol.26(6), pp.1746-1752
Hauptverfasser: CHIKUMA, TOSHIYUKI, NEGISHI, KAZUO, HAYATSU, HIKOYA
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Sprache:eng
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