Fused Pyrimidines. II. Synthesis and Oxidation of 3-Aminoisothiazolo [3, 4-d] pyrimidines
Reaction of 6-aminouracils (I) with alkyl or aryl isothiocyanates afforded 6-amino-5-substituted thiocarbamoyluracils (II), which were oxidized with bromine or hydrogen peroxide to afford 3-(substituted) aminoisothiazolo [3, 4-d] pyrimidin-4, 6-(5H, 7H)-diones (III). Alkylation of III afforded 3-(N,...
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| Veröffentlicht in: | Chemical & pharmaceutical bulletin 1976/05/25, Vol.24(5), pp.979-986 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
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