Chiral Glycolate Equivalents for the Asymmetric Synthesis of [alpha]-Hydroxycarbonyl Compounds

Chiral Glycolate Equivalents for the Asymmetric Synthesis of [alpha]-Hydroxycarbonyl Compounds

Chiral glycolic acid equivalents are used extensively for the enantioselective synthesis of α-hydroxycarbonyl compounds. Their efficacy in enolate reactions and their utility in synthetic applications are discussed, highlighting the relevance of these methods to natural product synthesis.

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Veröffentlicht in:Bulletin of the Chemical Society of Japan 2007-08, Vol.80 (8), p.1451
Hauptverfasser: V. Ley, Steven, D. Sheppard, Tom, M. Myers, Rebecca, S. Chorghade, Mukund
Format: Artikel
Sprache:eng
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Zusammenfassung:Chiral glycolic acid equivalents are used extensively for the enantioselective synthesis of α-hydroxycarbonyl compounds. Their efficacy in enolate reactions and their utility in synthetic applications are discussed, highlighting the relevance of these methods to natural product synthesis.
ISSN:0009-2673
1348-0634