Breeding of a Low Pyruvate-Producing Sake Yeast by Isolation of a Mutant Resistant to Ethyl [alpha]-Transcyanocinnamate, an Inhibitor of Mitochondrial Pyruvate Transport

Pyruvate is the key substance controlling the formation of diacetyl, acetaldehyde, and acetate during alcoholic fermentation. Here we report the breeding of a low pyruvate-producing sake yeast by isolation of a mutant resistant to ethyl α-transcyanocinnamate, an inhibitor of mitochondrial pyruvate t...

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Veröffentlicht in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2010-04, Vol.74 (4), p.843
Hauptverfasser: HORIE, Kenta, OBA, Takahiro, MOTOMURA, Saori, ISOGAI, Atsuko, YOSHIMURA, Takashi, TSUGE, Keisuke, KOGANEMARU, Kazuyoshi, KOBAYASHI, Genta, KITAGAKI, Hiroshi
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container_title Bioscience, biotechnology, and biochemistry
container_volume 74
creator HORIE, Kenta
OBA, Takahiro
MOTOMURA, Saori
ISOGAI, Atsuko
YOSHIMURA, Takashi
TSUGE, Keisuke
KOGANEMARU, Kazuyoshi
KOBAYASHI, Genta
KITAGAKI, Hiroshi
description Pyruvate is the key substance controlling the formation of diacetyl, acetaldehyde, and acetate during alcoholic fermentation. Here we report the breeding of a low pyruvate-producing sake yeast by isolation of a mutant resistant to ethyl α-transcyanocinnamate, an inhibitor of mitochondrial pyruvate transport. Mitochondrial function was involved in resistance to this substance and in the production of pyruvate by the mutants.
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title Breeding of a Low Pyruvate-Producing Sake Yeast by Isolation of a Mutant Resistant to Ethyl [alpha]-Transcyanocinnamate, an Inhibitor of Mitochondrial Pyruvate Transport
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