Inhibition of collagenases from mouse lung carcinoma cells by green tea catechins and black tea theaflavins

Theaflavin and theaflavin digallate, which are components of black tea were examined by in vitro invasion assay with mouse Lewis lung carcinoma LL2-Lu3 cells, which are highly metastatic. The compounds inhibited invasion by the tumor cells. Gelatin zymography showed that the cells secreted matrix me...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 1997-09, Vol.61 (9), p.1504-1506
Hauptverfasser:	Sazuka, M. (Shizuoka Univ. (Japan)), Imazawa, H, Shoji, Y, Mita, T, Hara, Y, Isemura, M
Format:	Artikel
Sprache:	eng
Schlagworte:	(−)-epigallocatechin gallate Animals Antioxidants - pharmacology Biflavonoids Biological and medical sciences Biotechnology Carcinoma - enzymology CATECHIN Catechin - analogs & derivatives Catechin - pharmacology CATECHINE CATEQUINA FLAVINES Free Radical Scavengers - pharmacology Gallic Acid - analogs & derivatives Gallic Acid - pharmacology General pharmacology invasion Lung Neoplasms - enzymology matrix metalloproteinase Matrix Metalloproteinase Inhibitors Medical sciences Mice Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments PROTEASAS PROTEASE PROTEASES TEA Tea - chemistry THE Theaflavin theaflavin digallate Tumor Cells, Cultured
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