Epigallocatechin Gallate (EGCG) Inhibits the Sulfation of 1-Naphthol in a Human Colon Carcinoma Cell Line, Caco-2

We have previously reported that epigallocatechin gallate (EGCG) strongly inhibits the in vitro phenol sulfotransferase (P-ST) activity of a human colon carcinoma cell line, Caco-2. In the present study, we examined the ability of EGCG to inhibit the sulfation of 1-naphthol in intact Caco-2 cells. S...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2001, Vol.24(9), pp.1076-1078
Hauptverfasser:	ISOZAKI, Takayo, TAMURA, Hiro-omi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Arylsulfotransferase - antagonists & inhibitors Biological and medical sciences Caco-2 Caco-2 Cells Catechin - analogs & derivatives Catechin - pharmacology Chromatography, High Pressure Liquid Depression, Chemical EGCG Enzyme Inhibitors - pharmacology General pharmacology green tea Humans inhibition Medical sciences Naphthols - metabolism Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Sulfates - metabolism sulfotransferase
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