Biodegradation and Drug Release of Chitosan Gel Beads in Subcutaneous Air Pouches of Mice

Chitosan (CS) gel beads were prepared in 10% amino acid solution (pH 9) and implanted into air pouches (AP) prepared subcutaneously on the dorsal surface of mice. No inflammatory response was observed, and degradation of the beads in the AP increased as their degree of deacetylation decreased. Degra...

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Veröffentlicht in:Biological & pharmaceutical bulletin 2001, Vol.24(2), pp.205-208
Hauptverfasser: KOFUJI, Kyoko, ITO, Tomohiro, MURATA, Yoshifumi, KAWASHIMA, Susumu
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Sprache:eng
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