Exclusive CX^sub 3^CR1 dependence of kidney DCs impacts glomerulonephritis progression

DCs and macrophages both express the chemokine receptor CX3CR1. Here, the authors have demonstrated that its ligand, CX^sub 3^CL1, is highly expressed in the murine kidney and intestine. CX^sub 3^CL1 deficiency markedly reduced DC numbers in the healthy and inflamed kidney cortex, and to a lesser de...

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Veröffentlicht in:	The Journal of clinical investigation 2013-10, Vol.123 (10), p.4242
Hauptverfasser:	Hochheiser, Katharina, Heuser, Christoph, Krause, Torsten A, Teteris, Simon, Ilias, Anissa, Weisheit, Christina, Hoss, Florian, Tittel, André P, Knolle, Percy A, Panzer, Ulf, Engel, Daniel R, Tharaux, Pierre-Louis, Kurts, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Biomedical research Chemokines Dependence E coli Homeostasis Lymphocytes Microscopy Recruitment Rodents Studies
Online-Zugang:	Volltext
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