Determination of Phenytoin and Its Major Metabolites in Human Serum by High-Performance Liquid Chromatography with Fluorescence Detection

A highly sensitive fluorometric high-performance liquid chromatographic method was developed for the simultaneous determination of phenytoin and its major metabolites [5-(3-hydroxyphenyl)-5-phenylhydantoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin]. After extracting these compounds and 5-(4-methylph...

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Veröffentlicht in:	Analytical Sciences 1999, Vol.15(4), pp.371-375
Hauptverfasser:	HARA, Shuuji, HAGIWARA, Jun, FUKUZAWA, Misa, ONO, Nobufumi, KURODA, Takeshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences General pharmacology Medical sciences Pharmacology. Drug treatments Physicochemical properties. Structure-activity relationships
Online-Zugang:	Volltext
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