Amino Acid Sequence Determination of Cyclic Peptides by Tandem Mass Spectrometry Coupled with Fast Atom Bombardment Ionization
The unambiguous amino acid sequence analysis of a cyclic decapeptide antibiotic, gramicidin S, was performed using the title method and a B2/E constant linked scanning technique. The methodolgy for the sequence analysis involves the structure determination by tandem mass spectrometry (MS/MS) of a sm...
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| Veröffentlicht in: | Journal of the Mass Spectrometry Society of Japan 1986, Vol.34(5), pp.307-319 |
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| container_end_page | 319 |
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| container_issue | 5 |
| container_start_page | 307 |
| container_title | Journal of the Mass Spectrometry Society of Japan |
| container_volume | 34 |
| creator | Nakamura, Takemichi Nagaki, Hidemi Kinoshita, Takeshi |
| description | The unambiguous amino acid sequence analysis of a cyclic decapeptide antibiotic, gramicidin S, was performed using the title method and a B2/E constant linked scanning technique. The methodolgy for the sequence analysis involves the structure determination by tandem mass spectrometry (MS/MS) of a small acylium ion containing two or three amino acid residues, and the stepwise extension of the analyzed sequence by use of a combination of MS/MS and linked scanning. |
| doi_str_mv | 10.5702/massspec.34.307 |
| format | Article |
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Mass Spectrom. Soc. Jpn.</addtitle><description>The unambiguous amino acid sequence analysis of a cyclic decapeptide antibiotic, gramicidin S, was performed using the title method and a B2/E constant linked scanning technique. The methodolgy for the sequence analysis involves the structure determination by tandem mass spectrometry (MS/MS) of a small acylium ion containing two or three amino acid residues, and the stepwise extension of the analyzed sequence by use of a combination of MS/MS and linked scanning.</description><subject>Amino acid sequence determination</subject><subject>Collisionally activated dissociation spectra</subject><subject>Cyclic peptide</subject><subject>Daughter ion</subject><subject>Fast atom bombardment</subject><subject>Metastable ion spectra</subject><subject>Precursor ion</subject><subject>Tandem mass spectrometry</subject><issn>1340-8097</issn><issn>1880-4225</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><recordid>eNpVUEtLAzEQXkTBWj17DXjeNq_dbI-1tSooCuo5ZJNZm9LdrEmK1IO_3Wi14GVmmPkezJdl5wSPCoHpuFUhhB70iPERw-IgG5CqwjmntDhMM-M4r_BEHGcnIaww5rQUYpB9TlvbOTTV1qAneNtApwHNIYJPexWt65Br0Gyr11ajR-ijNRBQvUXPqjPQovvkip6SbfSuhei3aOY2_RoMerdxiRYqRDSNrkWXrq2VNy10Ed26zn78iJ9mR41aBzj77cPsZXH1PLvJ7x6ub2fTu1zTioqcGsBUUyaYwZSQgpS0qhWGiakFAa5rKMpGg-JlRXVpJkQ1wCrScIyVFgWwYXax0-29S0-GKFdu47tkKQnn5YSWRSkSarxDae9C8NDI3ttW-a0kWH6HLP9ClozLFHJizHeMVYjqFfZ45aPVa_iHL34LFvuzXiovoWNf6z6MkQ</recordid><startdate>1986</startdate><enddate>1986</enddate><creator>Nakamura, Takemichi</creator><creator>Nagaki, Hidemi</creator><creator>Kinoshita, Takeshi</creator><general>The Mass Spectrometry Society of Japan</general><general>Japan Science and Technology Agency</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope></search><sort><creationdate>1986</creationdate><title>Amino Acid Sequence Determination of Cyclic Peptides by Tandem Mass Spectrometry Coupled with Fast Atom Bombardment Ionization</title><author>Nakamura, Takemichi ; Nagaki, Hidemi ; Kinoshita, Takeshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2827-2de02c2373d021151628ba0e9db71e4cbe56fcea4682c6d91afe381f400ac75e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Amino acid sequence determination</topic><topic>Collisionally activated dissociation spectra</topic><topic>Cyclic peptide</topic><topic>Daughter ion</topic><topic>Fast atom bombardment</topic><topic>Metastable ion spectra</topic><topic>Precursor ion</topic><topic>Tandem mass spectrometry</topic><toplevel>online_resources</toplevel><creatorcontrib>Nakamura, Takemichi</creatorcontrib><creatorcontrib>Nagaki, Hidemi</creatorcontrib><creatorcontrib>Kinoshita, Takeshi</creatorcontrib><collection>CrossRef</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Journal of the Mass Spectrometry Society of Japan</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nakamura, Takemichi</au><au>Nagaki, Hidemi</au><au>Kinoshita, Takeshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Amino Acid Sequence Determination of Cyclic Peptides by Tandem Mass Spectrometry Coupled with Fast Atom Bombardment Ionization</atitle><jtitle>Journal of the Mass Spectrometry Society of Japan</jtitle><addtitle>J. Mass Spectrom. Soc. Jpn.</addtitle><date>1986</date><risdate>1986</risdate><volume>34</volume><issue>5</issue><spage>307</spage><epage>319</epage><pages>307-319</pages><issn>1340-8097</issn><eissn>1880-4225</eissn><abstract>The unambiguous amino acid sequence analysis of a cyclic decapeptide antibiotic, gramicidin S, was performed using the title method and a B2/E constant linked scanning technique. The methodolgy for the sequence analysis involves the structure determination by tandem mass spectrometry (MS/MS) of a small acylium ion containing two or three amino acid residues, and the stepwise extension of the analyzed sequence by use of a combination of MS/MS and linked scanning.</abstract><cop>Tokyo</cop><pub>The Mass Spectrometry Society of Japan</pub><doi>10.5702/massspec.34.307</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1340-8097 |
| ispartof | Journal of the Mass Spectrometry Society of Japan, 1986, Vol.34(5), pp.307-319 |
| issn | 1340-8097 1880-4225 |
| language | eng |
| recordid | cdi_proquest_journals_1446926567 |
| source | J-STAGE Free; EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | Amino acid sequence determination Collisionally activated dissociation spectra Cyclic peptide Daughter ion Fast atom bombardment Metastable ion spectra Precursor ion Tandem mass spectrometry |
| title | Amino Acid Sequence Determination of Cyclic Peptides by Tandem Mass Spectrometry Coupled with Fast Atom Bombardment Ionization |
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