Radiosensitization by the Combination of SR-2508 and Paclitaxel in Hypoxic Human Tumor Cells in vitro

The two radiosensitizers SR-2508 (etanidazole) and paclitaxel (taxol) have different dose-limiting toxicities in humans. Combination of the two radiosensitizers may increase radiosensitization without increasing toxicity. This study was carried out to determine the synergistic radiosensitizing effec...

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Veröffentlicht in:	JOURNAL OF RADIATION RESEARCH 2007, Vol.48 (3), p.179-185
Hauptverfasser:	Jin, Cheng, Bai, Ling, Guo, Guozhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - administration & dosage Antineoplastic Combined Chemotherapy Protocols - administration & dosage Breast Neoplasms - pathology Cell Hypoxia - drug effects Cell Hypoxia - radiation effects Cell Line, Tumor Cell Survival - drug effects Cell Survival - radiation effects Dose-Response Relationship, Drug Dose-Response Relationship, Radiation Etanidazole - administration & dosage HeLa Cells Humans Paclitaxel - administration & dosage Radiation Dosage Radiation Tolerance - drug effects Radiation-Sensitizing Agents - administration & dosage
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