ARFI quantitative elastography of the submandibular glands. Normal measurements and the diagnosis value of the method in radiation submaxillitis
Evaluation of Acoustic Radiation Force Impulse Imaging (ARFI) elastography performance in predicting the elasticity of the submandibular glands in normal situations and after radiation therapy. A number of 54 normal submandibular glands from 27 voluntary subjects and 33 pathological submandibular gl...
Gespeichert in:
| Veröffentlicht in: | Medical ultrasonography 2013-09, Vol.15 (3), p.173-179 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 179 |
|---|---|
| container_issue | 3 |
| container_start_page | 173 |
| container_title | Medical ultrasonography |
| container_volume | 15 |
| creator | Badea, Alexandru Florin Tamas Szora, Attila Ciuleanu, Elisabeta Chioreanu, Ioana Băciuţ, Grigore Lupşor Platon, Monica Badea, Radu |
| description | Evaluation of Acoustic Radiation Force Impulse Imaging (ARFI) elastography performance in predicting the elasticity of the submandibular glands in normal situations and after radiation therapy.
A number of 54 normal submandibular glands from 27 voluntary subjects and 33 pathological submandibular glands (radiation submaxillities) from 18 patients who had undergone radiation therapy for various cervical and facial oncological conditions were included in study. All the patients had undergone a B mode ultrasonography (Tissue Harmonic Imaging, 8-14 MHz) while the submandibular volume was determined and subsequently an ARFI examination while the shear wave velocity (SWV) was measured (in the central, peripheral and subcapsular areas, with the results expressed in m/s).
In the volunteers' group the mean value of the SWV of the left submandibular gland was 1.68 ± 0.46 m/s, determined in the centre of the gland, 1.88 ± 0.4 m/s in the periphery (corresponding to the subcapsular parenchyma) and the SWV of the right submandibular gland was 1.74 ± 0.35 m/s (centrally) and 1.84 ± 0.43 m/s in the periphery. The mean value of all measurements was 1.82 ± 0.41 m/s. The mean volume of the glands was 7.97 ± 2.63 cm3. In the group of patients who had underwent radiation therapy (at least 35Gy), the mean value of the SWV was 2.24 ± 0.49 m/s centrally and 2.1 ± 0.58 m/s in the periphery on the left and 1.99 ± 0.5 m/s centrally and 2.21 ± 0.52 m/s in the periphery on the right. The mean value of all the measurements was 2.13 ± 0.52 m/s and the mean volume of the gland was 5.95 ± 4.16 cm3.
Elastography using ARFI technique is a valid examination in the evaluation of the normal and pathological submandibular gland stiffness. The values of the shear wave velocities that correspond to a normal stiffness, determined through the ARFI technique, are similar in the two glands. After cervical and facial radiation therapy the values of the SWV are increased, indicating a change in the consistency of the gland thus implying a structural transformation. The ARFI technique can be used in the evaluation of the salivary glands pathology. |
| doi_str_mv | 10.11152/mu.2013.2066.153.afb1ats2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1444149765</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3106659561</sourcerecordid><originalsourceid>FETCH-LOGICAL-c535t-ff6f3f5b084faf8af9bd3b801f3ca807b929965ec4a71e7f661933c85fffc3f3</originalsourceid><addsrcrecordid>eNo9Udtq3DAQFaWlWdL8QhHtsx2PdbHVtxCaJhBaKHkXY1vaVbGtjS6h-Yt8crXZbF9mhplzzjBzCPkCTQ0Aor1cct02wEqQsgbBarQDYIrtO7I59KpecvaebKDnvOLQtWfkIkY3NC0D2QnVfCRnLVOdkgAb8nL1--aOPmZck0uY3JOhZsaY_DbgfvdMvaVpZ2jMw4Lr5IY8Y6DbudSxpj99WHCmi8GYg1nMmiItk1fG5HC7-ugifcI5m5PQYtLOT9StNGCBJOfXo_hfN88uufiJfLA4R3Pxls_Jw833h-vb6v7Xj7vrq_tqFEykylppmRVD03OLtkerhokNfQOWjdg33aBapaQwI8cOTGelBMXY2Atr7cgsOydfj7L74B-ziUn_8TmsZaMGzjlw1UlRUN-OqDH4GIOxeh_cguFZQ6Nf7dBL1gc79OH1utihT3YU8ue3FeU-M_2nnp7P_gHkgYzr</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1444149765</pqid></control><display><type>article</type><title>ARFI quantitative elastography of the submandibular glands. Normal measurements and the diagnosis value of the method in radiation submaxillitis</title><source>MEDLINE</source><source>EZB Electronic Journals Library</source><creator>Badea, Alexandru Florin ; Tamas Szora, Attila ; Ciuleanu, Elisabeta ; Chioreanu, Ioana ; Băciuţ, Grigore ; Lupşor Platon, Monica ; Badea, Radu</creator><creatorcontrib>Badea, Alexandru Florin ; Tamas Szora, Attila ; Ciuleanu, Elisabeta ; Chioreanu, Ioana ; Băciuţ, Grigore ; Lupşor Platon, Monica ; Badea, Radu</creatorcontrib><description>Evaluation of Acoustic Radiation Force Impulse Imaging (ARFI) elastography performance in predicting the elasticity of the submandibular glands in normal situations and after radiation therapy.
A number of 54 normal submandibular glands from 27 voluntary subjects and 33 pathological submandibular glands (radiation submaxillities) from 18 patients who had undergone radiation therapy for various cervical and facial oncological conditions were included in study. All the patients had undergone a B mode ultrasonography (Tissue Harmonic Imaging, 8-14 MHz) while the submandibular volume was determined and subsequently an ARFI examination while the shear wave velocity (SWV) was measured (in the central, peripheral and subcapsular areas, with the results expressed in m/s).
In the volunteers' group the mean value of the SWV of the left submandibular gland was 1.68 ± 0.46 m/s, determined in the centre of the gland, 1.88 ± 0.4 m/s in the periphery (corresponding to the subcapsular parenchyma) and the SWV of the right submandibular gland was 1.74 ± 0.35 m/s (centrally) and 1.84 ± 0.43 m/s in the periphery. The mean value of all measurements was 1.82 ± 0.41 m/s. The mean volume of the glands was 7.97 ± 2.63 cm3. In the group of patients who had underwent radiation therapy (at least 35Gy), the mean value of the SWV was 2.24 ± 0.49 m/s centrally and 2.1 ± 0.58 m/s in the periphery on the left and 1.99 ± 0.5 m/s centrally and 2.21 ± 0.52 m/s in the periphery on the right. The mean value of all the measurements was 2.13 ± 0.52 m/s and the mean volume of the gland was 5.95 ± 4.16 cm3.
Elastography using ARFI technique is a valid examination in the evaluation of the normal and pathological submandibular gland stiffness. The values of the shear wave velocities that correspond to a normal stiffness, determined through the ARFI technique, are similar in the two glands. After cervical and facial radiation therapy the values of the SWV are increased, indicating a change in the consistency of the gland thus implying a structural transformation. The ARFI technique can be used in the evaluation of the salivary glands pathology.</description><identifier>ISSN: 1844-4172</identifier><identifier>EISSN: 2066-8643</identifier><identifier>DOI: 10.11152/mu.2013.2066.153.afb1ats2</identifier><identifier>PMID: 23979611</identifier><language>eng</language><publisher>Romania: Romanian Society of Ultrasonography in Medicine and Biology</publisher><subject>Adult ; Elasticity Imaging Techniques - methods ; Female ; Humans ; Image Enhancement - methods ; Image Interpretation, Computer-Assisted - methods ; Male ; Middle Aged ; Radiation Injuries - diagnostic imaging ; Radiation Injuries - etiology ; Radiotherapy, Conformal - adverse effects ; Reproducibility of Results ; Sensitivity and Specificity ; Sialadenitis - diagnostic imaging ; Sialadenitis - etiology ; Submandibular Gland Diseases - diagnostic imaging ; Submandibular Gland Diseases - etiology ; Young Adult</subject><ispartof>Medical ultrasonography, 2013-09, Vol.15 (3), p.173-179</ispartof><rights>Copyright Romanian Society of Ultrasonography in Medicine and Biology 2013</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c535t-ff6f3f5b084faf8af9bd3b801f3ca807b929965ec4a71e7f661933c85fffc3f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23979611$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Badea, Alexandru Florin</creatorcontrib><creatorcontrib>Tamas Szora, Attila</creatorcontrib><creatorcontrib>Ciuleanu, Elisabeta</creatorcontrib><creatorcontrib>Chioreanu, Ioana</creatorcontrib><creatorcontrib>Băciuţ, Grigore</creatorcontrib><creatorcontrib>Lupşor Platon, Monica</creatorcontrib><creatorcontrib>Badea, Radu</creatorcontrib><title>ARFI quantitative elastography of the submandibular glands. Normal measurements and the diagnosis value of the method in radiation submaxillitis</title><title>Medical ultrasonography</title><addtitle>Med Ultrason</addtitle><description>Evaluation of Acoustic Radiation Force Impulse Imaging (ARFI) elastography performance in predicting the elasticity of the submandibular glands in normal situations and after radiation therapy.
A number of 54 normal submandibular glands from 27 voluntary subjects and 33 pathological submandibular glands (radiation submaxillities) from 18 patients who had undergone radiation therapy for various cervical and facial oncological conditions were included in study. All the patients had undergone a B mode ultrasonography (Tissue Harmonic Imaging, 8-14 MHz) while the submandibular volume was determined and subsequently an ARFI examination while the shear wave velocity (SWV) was measured (in the central, peripheral and subcapsular areas, with the results expressed in m/s).
In the volunteers' group the mean value of the SWV of the left submandibular gland was 1.68 ± 0.46 m/s, determined in the centre of the gland, 1.88 ± 0.4 m/s in the periphery (corresponding to the subcapsular parenchyma) and the SWV of the right submandibular gland was 1.74 ± 0.35 m/s (centrally) and 1.84 ± 0.43 m/s in the periphery. The mean value of all measurements was 1.82 ± 0.41 m/s. The mean volume of the glands was 7.97 ± 2.63 cm3. In the group of patients who had underwent radiation therapy (at least 35Gy), the mean value of the SWV was 2.24 ± 0.49 m/s centrally and 2.1 ± 0.58 m/s in the periphery on the left and 1.99 ± 0.5 m/s centrally and 2.21 ± 0.52 m/s in the periphery on the right. The mean value of all the measurements was 2.13 ± 0.52 m/s and the mean volume of the gland was 5.95 ± 4.16 cm3.
Elastography using ARFI technique is a valid examination in the evaluation of the normal and pathological submandibular gland stiffness. The values of the shear wave velocities that correspond to a normal stiffness, determined through the ARFI technique, are similar in the two glands. After cervical and facial radiation therapy the values of the SWV are increased, indicating a change in the consistency of the gland thus implying a structural transformation. The ARFI technique can be used in the evaluation of the salivary glands pathology.</description><subject>Adult</subject><subject>Elasticity Imaging Techniques - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Image Enhancement - methods</subject><subject>Image Interpretation, Computer-Assisted - methods</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Radiation Injuries - diagnostic imaging</subject><subject>Radiation Injuries - etiology</subject><subject>Radiotherapy, Conformal - adverse effects</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Sialadenitis - diagnostic imaging</subject><subject>Sialadenitis - etiology</subject><subject>Submandibular Gland Diseases - diagnostic imaging</subject><subject>Submandibular Gland Diseases - etiology</subject><subject>Young Adult</subject><issn>1844-4172</issn><issn>2066-8643</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNo9Udtq3DAQFaWlWdL8QhHtsx2PdbHVtxCaJhBaKHkXY1vaVbGtjS6h-Yt8crXZbF9mhplzzjBzCPkCTQ0Aor1cct02wEqQsgbBarQDYIrtO7I59KpecvaebKDnvOLQtWfkIkY3NC0D2QnVfCRnLVOdkgAb8nL1--aOPmZck0uY3JOhZsaY_DbgfvdMvaVpZ2jMw4Lr5IY8Y6DbudSxpj99WHCmi8GYg1nMmiItk1fG5HC7-ugifcI5m5PQYtLOT9StNGCBJOfXo_hfN88uufiJfLA4R3Pxls_Jw833h-vb6v7Xj7vrq_tqFEykylppmRVD03OLtkerhokNfQOWjdg33aBapaQwI8cOTGelBMXY2Atr7cgsOydfj7L74B-ziUn_8TmsZaMGzjlw1UlRUN-OqDH4GIOxeh_cguFZQ6Nf7dBL1gc79OH1utihT3YU8ue3FeU-M_2nnp7P_gHkgYzr</recordid><startdate>20130901</startdate><enddate>20130901</enddate><creator>Badea, Alexandru Florin</creator><creator>Tamas Szora, Attila</creator><creator>Ciuleanu, Elisabeta</creator><creator>Chioreanu, Ioana</creator><creator>Băciuţ, Grigore</creator><creator>Lupşor Platon, Monica</creator><creator>Badea, Radu</creator><general>Romanian Society of Ultrasonography in Medicine and Biology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BYOGL</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20130901</creationdate><title>ARFI quantitative elastography of the submandibular glands. Normal measurements and the diagnosis value of the method in radiation submaxillitis</title><author>Badea, Alexandru Florin ; Tamas Szora, Attila ; Ciuleanu, Elisabeta ; Chioreanu, Ioana ; Băciuţ, Grigore ; Lupşor Platon, Monica ; Badea, Radu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c535t-ff6f3f5b084faf8af9bd3b801f3ca807b929965ec4a71e7f661933c85fffc3f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Elasticity Imaging Techniques - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Image Enhancement - methods</topic><topic>Image Interpretation, Computer-Assisted - methods</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Radiation Injuries - diagnostic imaging</topic><topic>Radiation Injuries - etiology</topic><topic>Radiotherapy, Conformal - adverse effects</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Sialadenitis - diagnostic imaging</topic><topic>Sialadenitis - etiology</topic><topic>Submandibular Gland Diseases - diagnostic imaging</topic><topic>Submandibular Gland Diseases - etiology</topic><topic>Young Adult</topic><toplevel>online_resources</toplevel><creatorcontrib>Badea, Alexandru Florin</creatorcontrib><creatorcontrib>Tamas Szora, Attila</creatorcontrib><creatorcontrib>Ciuleanu, Elisabeta</creatorcontrib><creatorcontrib>Chioreanu, Ioana</creatorcontrib><creatorcontrib>Băciuţ, Grigore</creatorcontrib><creatorcontrib>Lupşor Platon, Monica</creatorcontrib><creatorcontrib>Badea, Radu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>East Europe, Central Europe Database</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest advanced technologies & aerospace journals</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Medical ultrasonography</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Badea, Alexandru Florin</au><au>Tamas Szora, Attila</au><au>Ciuleanu, Elisabeta</au><au>Chioreanu, Ioana</au><au>Băciuţ, Grigore</au><au>Lupşor Platon, Monica</au><au>Badea, Radu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>ARFI quantitative elastography of the submandibular glands. Normal measurements and the diagnosis value of the method in radiation submaxillitis</atitle><jtitle>Medical ultrasonography</jtitle><addtitle>Med Ultrason</addtitle><date>2013-09-01</date><risdate>2013</risdate><volume>15</volume><issue>3</issue><spage>173</spage><epage>179</epage><pages>173-179</pages><issn>1844-4172</issn><eissn>2066-8643</eissn><abstract>Evaluation of Acoustic Radiation Force Impulse Imaging (ARFI) elastography performance in predicting the elasticity of the submandibular glands in normal situations and after radiation therapy.
A number of 54 normal submandibular glands from 27 voluntary subjects and 33 pathological submandibular glands (radiation submaxillities) from 18 patients who had undergone radiation therapy for various cervical and facial oncological conditions were included in study. All the patients had undergone a B mode ultrasonography (Tissue Harmonic Imaging, 8-14 MHz) while the submandibular volume was determined and subsequently an ARFI examination while the shear wave velocity (SWV) was measured (in the central, peripheral and subcapsular areas, with the results expressed in m/s).
In the volunteers' group the mean value of the SWV of the left submandibular gland was 1.68 ± 0.46 m/s, determined in the centre of the gland, 1.88 ± 0.4 m/s in the periphery (corresponding to the subcapsular parenchyma) and the SWV of the right submandibular gland was 1.74 ± 0.35 m/s (centrally) and 1.84 ± 0.43 m/s in the periphery. The mean value of all measurements was 1.82 ± 0.41 m/s. The mean volume of the glands was 7.97 ± 2.63 cm3. In the group of patients who had underwent radiation therapy (at least 35Gy), the mean value of the SWV was 2.24 ± 0.49 m/s centrally and 2.1 ± 0.58 m/s in the periphery on the left and 1.99 ± 0.5 m/s centrally and 2.21 ± 0.52 m/s in the periphery on the right. The mean value of all the measurements was 2.13 ± 0.52 m/s and the mean volume of the gland was 5.95 ± 4.16 cm3.
Elastography using ARFI technique is a valid examination in the evaluation of the normal and pathological submandibular gland stiffness. The values of the shear wave velocities that correspond to a normal stiffness, determined through the ARFI technique, are similar in the two glands. After cervical and facial radiation therapy the values of the SWV are increased, indicating a change in the consistency of the gland thus implying a structural transformation. The ARFI technique can be used in the evaluation of the salivary glands pathology.</abstract><cop>Romania</cop><pub>Romanian Society of Ultrasonography in Medicine and Biology</pub><pmid>23979611</pmid><doi>10.11152/mu.2013.2066.153.afb1ats2</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1844-4172 |
| ispartof | Medical ultrasonography, 2013-09, Vol.15 (3), p.173-179 |
| issn | 1844-4172 2066-8643 |
| language | eng |
| recordid | cdi_proquest_journals_1444149765 |
| source | MEDLINE; EZB Electronic Journals Library |
| subjects | Adult Elasticity Imaging Techniques - methods Female Humans Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Male Middle Aged Radiation Injuries - diagnostic imaging Radiation Injuries - etiology Radiotherapy, Conformal - adverse effects Reproducibility of Results Sensitivity and Specificity Sialadenitis - diagnostic imaging Sialadenitis - etiology Submandibular Gland Diseases - diagnostic imaging Submandibular Gland Diseases - etiology Young Adult |
| title | ARFI quantitative elastography of the submandibular glands. Normal measurements and the diagnosis value of the method in radiation submaxillitis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-13T22%3A59%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=ARFI%20quantitative%20elastography%20of%20the%20submandibular%20glands.%20Normal%20measurements%20and%20the%20diagnosis%20value%20of%20the%20method%20in%20radiation%20submaxillitis&rft.jtitle=Medical%20ultrasonography&rft.au=Badea,%20Alexandru%20Florin&rft.date=2013-09-01&rft.volume=15&rft.issue=3&rft.spage=173&rft.epage=179&rft.pages=173-179&rft.issn=1844-4172&rft.eissn=2066-8643&rft_id=info:doi/10.11152/mu.2013.2066.153.afb1ats2&rft_dat=%3Cproquest_cross%3E3106659561%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1444149765&rft_id=info:pmid/23979611&rfr_iscdi=true |