Quorum Sensing and Morphological Regulation in the Pathogenic Fungus Candida albicans
Quorum sensing is a cell-density effect and the regulation of gene expression in response to extracellular chemical signals (quorum-sensing molecules) produced by microorganisms. Hyphal induction in Candid albicans is inhibited by high cell density and also by farnesol, which is a quorum-sensing mol...
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Veröffentlicht in: | Journal of oral biosciences 2010-01, Vol.52 (3), p.233-239 |
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container_title | Journal of oral biosciences |
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creator | Cho, Tamaki Nagao, Jun-ichi Imayoshi, Rieko Kaminishi, Hidenori Aoyama, Toshihiro Nakayama, Hironobu |
description | Quorum sensing is a cell-density effect and the regulation of gene expression in response to extracellular chemical signals (quorum-sensing molecules) produced by microorganisms. Hyphal induction in Candid albicans is inhibited by high cell density and also by farnesol, which is a quorum-sensing molecule of the organism. Here, we describe models of the regulation of dimorphism in Candida albicans by farnesol from the latest published data and gene regulation during the initial stages of quorum sensing, which was obtained through microarray analysis. |
doi_str_mv | 10.1016/S1349-0079(10)80026-X |
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Here, we describe models of the regulation of dimorphism in Candida albicans by farnesol from the latest published data and gene regulation during the initial stages of quorum sensing, which was obtained through microarray analysis.</description><subject>Candida albicans</subject><subject>cell density</subject><subject>farnesol</subject><subject>quorum sensing</subject><issn>1349-0079</issn><issn>1880-3865</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNqFkE1LAzEURYMoWKs_QQi40cVoMpmPzEqkWBUqftRCdyFN3kxTpklNZgT_vWmra1d5hHvu4x2Ezim5poQWN1PKsiohpKwuKbnihKRFMj9AA8o5SRgv8sM4_0WO0UkIK0JYxXI2QLO33vl-jadgg7ENllbjZ-c3S9e6xijZ4ndo-lZ2xllsLO6WgF9lt3QNWKPwuLdNH_AoYkZLLNtFZGw4RUe1bAOc_b5DNBvff4wek8nLw9PobpKotEx5IqGuC5WVi1SBlJzWtFxwkhecl3laaApQAywKVVUcpNZUc1LJMpeaKV3loNgQXex7N9599hA6sXK9t3GloFmWUUZjV0zl-5TyLgQPtdh4s5b-W1AitgbFzqDY6tl-7QyKeeRu9xzEE74MeBGUAatAGw-qE9qZfxp-AJT3ebw</recordid><startdate>201001</startdate><enddate>201001</enddate><creator>Cho, Tamaki</creator><creator>Nagao, Jun-ichi</creator><creator>Imayoshi, Rieko</creator><creator>Kaminishi, Hidenori</creator><creator>Aoyama, Toshihiro</creator><creator>Nakayama, Hironobu</creator><general>Elsevier B.V</general><general>Elsevier Limited</general><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope></search><sort><creationdate>201001</creationdate><title>Quorum Sensing and Morphological Regulation in the Pathogenic Fungus Candida albicans</title><author>Cho, Tamaki ; Nagao, Jun-ichi ; Imayoshi, Rieko ; Kaminishi, Hidenori ; Aoyama, Toshihiro ; Nakayama, Hironobu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2728-aeff6c47b2ceaa81f17b8056887526d1eefeeb6c998eadd1d809a75ad3cd95ec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Candida albicans</topic><topic>cell density</topic><topic>farnesol</topic><topic>quorum sensing</topic><toplevel>online_resources</toplevel><creatorcontrib>Cho, Tamaki</creatorcontrib><creatorcontrib>Nagao, Jun-ichi</creatorcontrib><creatorcontrib>Imayoshi, Rieko</creatorcontrib><creatorcontrib>Kaminishi, Hidenori</creatorcontrib><creatorcontrib>Aoyama, Toshihiro</creatorcontrib><creatorcontrib>Nakayama, Hironobu</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Journal of oral biosciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cho, Tamaki</au><au>Nagao, Jun-ichi</au><au>Imayoshi, Rieko</au><au>Kaminishi, Hidenori</au><au>Aoyama, Toshihiro</au><au>Nakayama, Hironobu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quorum Sensing and Morphological Regulation in the Pathogenic Fungus Candida albicans</atitle><jtitle>Journal of oral biosciences</jtitle><date>2010-01</date><risdate>2010</risdate><volume>52</volume><issue>3</issue><spage>233</spage><epage>239</epage><pages>233-239</pages><issn>1349-0079</issn><eissn>1880-3865</eissn><abstract>Quorum sensing is a cell-density effect and the regulation of gene expression in response to extracellular chemical signals (quorum-sensing molecules) produced by microorganisms. 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subjects | Candida albicans cell density farnesol quorum sensing |
title | Quorum Sensing and Morphological Regulation in the Pathogenic Fungus Candida albicans |
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