Essential Role of Ascorbic Acid in Neural Differentiation and Development

Essential Role of Ascorbic Acid in Neural Differentiation and Development

The aim of this study was to investigate the role of ascorbic acid (AsA) in neural differentiation induced by nerve growth factor (NGF) in PC12 cells, a neural precursor cell line. Cells were cultivated in the presence of L-ascorbic acid-2-O-α-D-glucopyranoside (AA-2G) and evaluated for potentiation...

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Veröffentlicht in:Journal of health science (Tokyo, Japan) Japan), 2008-01, Vol.54 (1), p.43
Hauptverfasser: Haramoto, Mari, Tatemoto, Hideki, Muto, Norio
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creator Haramoto, Mari
Tatemoto, Hideki
Muto, Norio
description The aim of this study was to investigate the role of ascorbic acid (AsA) in neural differentiation induced by nerve growth factor (NGF) in PC12 cells, a neural precursor cell line. Cells were cultivated in the presence of L-ascorbic acid-2-O-α-D-glucopyranoside (AA-2G) and evaluated for potentiation of neural differentiation induced by a small amount of NGF. AA-2G enhanced the proportion of neurite-bearing cells in a concentration-dependent manner (
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title Essential Role of Ascorbic Acid in Neural Differentiation and Development
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