Hypoxic Regulation of Hand1 Controls the Fetal-Neonatal Switch in Cardiac Metabolism: e1001666

Cardiomyocytes are vulnerable to hypoxia in the adult, but adapted to hypoxia in utero. Current understanding of endogenous cardiac oxygen sensing pathways is limited. Myocardial oxygen consumption is determined by regulation of energy metabolism, which shifts from glycolysis to lipid oxidation soon...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	PLoS biology 2013-09, Vol.11 (9)
Hauptverfasser:	Breckenridge, Ross A, Piotrowska, Izabela, Ng, Keat-Eng, Ragan, Timothy J, West, James A, Kotecha, Surendra, Towers, Norma, Bennett, Michael, Kienesberger, Petra C, Smolenski, Ryszard T, Siddall, Hillary K, Offer, John L, Mocanu, Mihaela M, Yelon, Derek M, Dyck, Jason RB, Griffin, Jules L, Abramov, Andrey Y, Gould, Alex P, Mohun, Timothy J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiomyocytes Enzymes Gene expression Heart attacks Heart failure Heart surgery Hypoxia Lipids Metabolism Metabolites Ontology Proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!