Ionizing Radiation Leads to the Replacement and de novo Production of Colonic Lgr5^sup +^ Stem Cells

Tissue stem cells have self-renewal capability throughout their whole life, which is high enough to lead to the accumulation of DNA damage in a stem cell pool. Whether radiation-induced damage accumulates in tissue stem cells remains unknown, it could be investigated if the fate of the tissue stem c...

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Veröffentlicht in:	Radiation research 2013-06, Vol.179 (6), p.637
Hauptverfasser:	Otsuka, Kensuke, Hamada, Nobuyuki, Magae, Junji, Matsumoto, Hideki, Hoshi, Yuko, Iwasaki, Toshiyasu
Format:	Artikel
Sprache:	eng
Schlagworte:	Ionizing radiation Irradiation Stem cells
Online-Zugang:	Volltext
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