Development and validation of a rapid and sensitive assay for the determination of anisodamine in 50 µL of beagle dog plasma by LC-MS/MS

A simple, rapid, high-throughput, and highly sensitive LC-MS/MS was developed to determine anisodamine in a small volume (50 µL) of beagle dog plasma using atropine sulfate as the internal standard. The analyte and internal standard were isolated from 50 µL plasma samples after a one-step protein pr...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of separation science 2013-10, Vol.36 (19), p.3184
Hauptverfasser:	Li, Wenxue, Wen, Jun, He, Jingyu, Cao, Di, Sun, Fanlu, Li, Jinying, Fan, Guorong
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioassays Dogs Kinetics Pharmacology Plasma
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!