Design of tablets for the delayed and complete release of poorly water-soluble weak base drugs using SBE7M-[beta]-CD as a solubilizing agent

The challenge of designing a delayed-release oral dosage form is significantly increased when the drug substance is poorly water soluble. This manuscript describes the design and characterization of a novel controlled-release film-coated tablet for the pH-triggered delayed and complete release of po...

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Veröffentlicht in:	Journal of pharmaceutical sciences 2011-04, Vol.100 (4), p.1576
Hauptverfasser:	Rao, Venkatramana M, Zannou, Erika A, Stella, Valentino J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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