Circulating miR-22, miR-24 and miR-34a as Novel Predictive Biomarkers to Pemetrexed-Based Chemotherapy in Advanced Non-Small Cell Lung Cancer

Pemetrexed has been widely used in patients with advanced non‐small cell lung cancer (NSCLC). The clinical relevance of polymorphisms of folate pathway genes for pemetrexed metabolism have not been fully elucidated yet. The aim of this study was to evaluate the expression levels of circulating miR‐2...

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Veröffentlicht in:	Journal of cellular physiology 2014-01, Vol.229 (1), p.97-99
Hauptverfasser:	Franchina, Tindara, Amodeo, Valeria, Bronte, Giuseppe, Savio, Giuseppina, Ricciardi, Giuseppina R.R., Picciotto, Maria, Russo, Antonio, Giordano, Antonio, Adamo, Vincenzo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biomarkers, Pharmacological - blood Biomarkers, Tumor Blood Carcinoma, Non-Small-Cell Lung - blood Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - pathology Chemotherapy Female Gene Expression Regulation, Neoplastic - drug effects Glutamates - administration & dosage Guanine - administration & dosage Guanine - analogs & derivatives Humans Lung cancer Male MicroRNAs - blood Middle Aged Neoplasm Staging Neoplastic Cells, Circulating - metabolism Pemetrexed Prognosis
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