SCF Promotes Dental Pulp Progenitor Migration, Neovascularization, and Collagen Remodeling – Potential Applications as a Homing Factor in Dental Pulp Regeneration

Stem cell factor (SCF) is a powerful chemokine that binds to the c-Kit receptor CD117 and has shown promise as a homing agent capable of progenitor cell recruitment. In the present study we have documented high levels of both SCF and its receptor c-Kit in differentiating dental pulp (DP) cells and i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Stem cell reviews 2013-10, Vol.9 (5), p.655-667
Hauptverfasser:	Pan, Shuang, Dangaria, Smit, Gopinathan, Gokul, Yan, Xiulin, Lu, Xuanyu, Kolokythas, Antonia, Niu, Yumei, Luan, Xianghong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Animals Biomedical and Life Sciences Biomedical Engineering and Bioengineering Blotting, Western Cell Biology Cell Movement - drug effects Cell Movement - genetics Cells, Cultured Child Collagen - metabolism Cyclin D3 - genetics Cyclin D3 - metabolism Cyclin-Dependent Kinase 4 - genetics Cyclin-Dependent Kinase 4 - metabolism Dental Pulp - cytology Dental Pulp - metabolism Dental Pulp - physiology Extracellular Signal-Regulated MAP Kinases - metabolism Gene Expression Regulation, Developmental - drug effects Humans Life Sciences Mesenchymal Stem Cell Transplantation - methods Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - metabolism Mice Mice, Nude Neovascularization, Physiologic - drug effects Neovascularization, Physiologic - genetics Phosphatidylinositol 3-Kinases - metabolism Proto-Oncogene Proteins c-kit - metabolism Regeneration - drug effects Regeneration - genetics Regenerative Medicine/Tissue Engineering Reverse Transcriptase Polymerase Chain Reaction Signal Transduction - drug effects Stem Cell Factor - genetics Stem Cell Factor - metabolism Stem Cell Factor - pharmacology Stem Cells Transplantation, Heterologous
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!