Deferoxamine-induced dysplasia-like skeletal abnormalities at radiography and MRI

Background Current thalassemia major treatment includes blood transfusion and iron chelation, which is associated with growth disturbances and radiographic changes in the long bone metaphyses. Objective To explore and discuss the spectrum of deferoxamine-induced bone-dysplasia-like changes in childr...

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Veröffentlicht in:	Pediatric radiology 2013-09, Vol.43 (9), p.1159-1165
Hauptverfasser:	Seif El Dien, Hadeel M., Esmail, Reem I., Magdy, Rania E., Lotfy, Hala M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult beta-Thalassemia - complications beta-Thalassemia - drug therapy Bone Diseases, Developmental - chemically induced Bone Diseases, Developmental - diagnosis Chelating Agents - adverse effects Child Child, Preschool Deferoxamine - adverse effects Deferoxamine - therapeutic use Female Humans Imaging Magnetic Resonance Imaging - methods Male Medicine Medicine & Public Health Neuroradiology Nuclear Medicine Oncology Original Article Pediatrics Radiology Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed - methods Ultrasound Young Adult
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