Easy One-Pot Synthesis of 1-Monosubstituted Aliphatic 1,2,3-Triazoles from Aliphatic Halides, Sodium Azide and Propiolic Acid by a Click Cycloaddition/Decarboxylation Process

1-Monosubstituted aliphatic 1,2,3-triazoles were synthesized by a one-pot reaction from aliphatic halides （C1 and Br）, sodium azide and propiolic acid. The yields ranged from moderate to good. The reaction was easily carried out in DMF with Cs2CO3 at 100 ℃ by copper-catalyzed click cycloaddition/dec...

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Veröffentlicht in:	Chinese journal of chemistry 2013-08, Vol.31 (8), p.1011-1014
Hauptverfasser:	Zhang, Zhongkui, Kuang, Chunxiang
Format:	Artikel
Sprache:	eng
Schlagworte:	1-monosubstitued aliphatic 1 1‐monosubstitued aliphatic 1,2,3‐triazole 3-triazole click chemistry copper-catalyzed decarboxylation 一锅合成 三唑衍生物 丙炔酸 单取代 卤化物 叠氮化钠 环加成 脂肪族
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