Gremlin aggravates hyperglycemia-induced podocyte injury by a TGF[beta]/smad dependent signaling pathway

Gremlin is a bone morphogenic protein (BMP) antagonist and is elevated in diabetic kidney tissues. In the early course of diabetic nephropathy (DN), podocyte are injured. We studied the protein and gene expression of gremlin in mice podocytes cultured in hyperglycemia ambient. The role of gremlin on...

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Veröffentlicht in:	Journal of cellular biochemistry 2013-09, Vol.114 (9), p.2101
Hauptverfasser:	Li, Guiying, Li, Ying, Liu, Shuxia, Shi, Yonghong, Chi, Yanqing, Liu, Guijing, Shan, Tieying
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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