Safety, Pharmacokinetic, and Efficacy Studies of Oral DB868 in a First Stage Vervet Monkey Model of Human African Trypanosomiasis: e2230

There are no oral drugs for human African trypanosomiasis (HAT, sleeping sickness). A successful oral drug would have the potential to reduce or eliminate the need for patient hospitalization, thus reducing healthcare costs of HAT. The development of oral medications is a key objective of the Consor...

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Veröffentlicht in:	PLoS neglected tropical diseases 2013-06, Vol.7 (6)
Hauptverfasser:	Thuita, John K, Wolf, Kristina K, Murilla, Grace A, Liu, Qiang, Mutuku, James N, Chen, Yao, Bridges, Arlene S, Echi, Raymond, Ismail, Mohamed A, Ching, Shelley, Boykin, David W, Hall, James Edwin, Tidwell, Richard R, Paine, Mary F, Brun, Reto, Wang, Michael Zhuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug dosages Drug therapy Infections Pharmaceutical industry Pharmacokinetics Plasma Tropical diseases Urea Vector-borne diseases
Online-Zugang:	Volltext
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