C/EBP[alpha] and MYB regulate FLT3 expression in AML

The interaction between the receptor FLT3 (FMS-like tyrosine kinase-3) and its ligand FL leads to crucial signalling during the early stages of the commitment of haematopoietic stem cells. Mutation or over-expression of the FLT3 gene, leading to constitutive signalling, enhances the survival and exp...

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Veröffentlicht in:	Leukemia 2013-07, Vol.27 (7), p.1487
Hauptverfasser:	Volpe, G, Walton, D S, Del Pozzo, W, Garcia, P, Dassé, E, O'neill, L P, Griffiths, M, Frampton, J, Dumon, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical research Cooperation Gene expression Kinases Leukemia Ligands Medical prognosis Mutation Proteins Stem cells
Online-Zugang:	Volltext
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