Aspirin enhances IFN-[alpha]-induced growth inhibition and apoptosis of hepatocellular carcinoma via JAK1/STAT1 pathway

STAT1 has a key role in exerting the antiproliferative and proapoptotic effects of interferon (IFN)-α on tumors, and its defects in expression is associated with IFN-α resistance. In this study we want to investigate whether aspirin can improve the antitumor efficiency of IFN-α on hepatocellular car...

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Veröffentlicht in:Cancer gene therapy 2013-06, Vol.20 (6), p.366
Hauptverfasser: Li, T, Dong, Z-r, Guo, Z-y, Wang, C-h, Tang, Z-y, Qu, S-f, Chen, Z-t, Li, X-w, Zhi, X-t
Format: Artikel
Sprache:eng
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