Antagonism of the histamine H^sub 4^ receptor reduces LPS-induced TNF production in vivo

Antagonism of the histamine H^sub 4^ receptor (H^sub 4^R) has been shown to be anti-inflammatory in a number of preclinical disease models, however the exact mechanisms behind this are still being uncovered. In vitro, the receptor interacts with TLR and impacts inflammatory mediator production from...

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Veröffentlicht in:	Inflammation research 2013-06, Vol.62 (6), p.599
Hauptverfasser:	Cowden, Jeffery M, Yu, Fuqu, Challapalli, Mamatha, Huang, Jing-feng, Kim, Sunhwa, Fung-leung, Wai-ping, Ma, Jing Ying, Riley, Jason P, Zhang, Mai, Dunford, Paul J, Thurmond, Robin L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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