Optical Purifications via Self-Disproportionation of Enantiomers by Achiral Chromatography: Case Study of a Series of [alpha]-CF3-containing Secondary Alcohols

Optical Purifications via Self-Disproportionation of Enantiomers by Achiral Chromatography: Case Study of a Series of [alpha]-CF3-containing Secondary Alcohols

This work demonstrates that self-disproportionation of enantiomers via achiral chromatography can be recommended as inexpensive and general method for optical purification of enantiomerically enriched compounds. In particular, the advantage of this approach over conventional recrystallization is tha...

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Veröffentlicht in:Chirality (New York, N.Y.) N.Y.), 2013-06, Vol.25 (6), p.365
Hauptverfasser: Sorochinsky, Alexander E, Katagiri, Toshimasa, Ono, Taizo, Wzorek, Alicja, Aceña, José Luis, Soloshonok, Vadim A
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Sprache:eng
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Zusammenfassung:This work demonstrates that self-disproportionation of enantiomers via achiral chromatography can be recommended as inexpensive and general method for optical purification of enantiomerically enriched compounds. In particular, the advantage of this approach over conventional recrystallization is that it can be used for both crystalline as well as liquid compounds. Chirality, 25:365-368, 2013. © 2013 Wiley Periodicals, Inc. [PUBLICATION ABSTRACT]
ISSN:0899-0042
1520-636X
DOI:10.1002/chir.22180