Vascular function and atherosclerosis progression after 1 y of flavonoid intake in statin-treated postmenopausal women with type 2 diabetes: a double-blind randomized controlled trial

Background: In healthy participants, short-term flavan-3-ol and isoflavone intakes improve vascular function; however, the potential combined benefit of these compounds on atherosclerosis progression remains unclear for those at elevated risk of cardiovascular disease.Objective: The objective was to...

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Veröffentlicht in:	The American journal of clinical nutrition 2013-05, Vol.97 (5), p.936-942
Hauptverfasser:	Curtis, Peter J, Potter, John, Kroon, Paul A, Wilson, Paddy, Dhatariya, Ketan, Sampson, Mike, Cassidy, Aedín
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Arterial Pressure - drug effects Atherosclerosis Atherosclerosis (general aspects, experimental research) Atherosclerosis - drug therapy Atherosclerosis - physiopathology Biological and medical sciences biomarkers Biomarkers - blood Blood and lymphatic vessels blood pressure Cardiology. Vascular system Cardiovascular disease carotid arteries Carotid Artery, Common - drug effects Carotid Intima-Media Thickness chocolate clinical nutrition Diabetes Diabetes Mellitus, Type 2 - physiopathology Diabetes. Impaired glucose tolerance Diet Disease Progression Double-Blind Method Endocrine pancreas. Apud cells (diseases) Endocrinopathies epicatechin Etiopathogenesis. Screening. Investigations. Target tissue resistance Feeding. Feeding behavior Female Flavonoids - administration & dosage Fundamental and applied biological sciences. Psychology Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use isoflavones Isoflavones - administration & dosage Medical sciences Menopause Middle Aged noninsulin-dependent diabetes mellitus Patient Compliance patients Postmenopause Pulse Wave Analysis randomized clinical trials risk Risk assessment risk reduction Statins Vascular Stiffness - drug effects Vertebrates: anatomy and physiology, studies on body, several organs or systems Women
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