A short-term n-3 DPA supplementation study in humans
Purpose Despite the detailed knowledge of the absorption and incorporation of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) into plasma lipids and red blood cells (RBC) in humans, very little is known about docosapentaenoic acid (DPA, 22:5 n-3). The aim of this study was to investigate...
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| Veröffentlicht in: | European journal of nutrition 2013-04, Vol.52 (3), p.895-904 |
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| container_title | European journal of nutrition |
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| creator | Miller, Eliza Kaur, Gunveen Larsen, Amy Loh, Su Peng Linderborg, Kaisa Weisinger, Harrison S. Turchini, Giovanni M. Cameron-Smith, David Sinclair, Andrew J. |
| description | Purpose
Despite the detailed knowledge of the absorption and incorporation of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) into plasma lipids and red blood cells (RBC) in humans, very little is known about docosapentaenoic acid (DPA, 22:5 n-3). The aim of this study was to investigate the uptake and incorporation of pure DPA and EPA into human plasma and RBC lipids.
Methods
Ten female participants received 8 g of pure DPA or pure EPA in randomized crossover double-blinded manner over a 7-day period. The placebo treatment was olive oil. Blood samples were collected at days zero, four and seven, following which the plasma and RBC were separated and used for the analysis of fatty acids.
Results
Supplementation with DPA significantly increased the proportions of DPA in the plasma phospholipids (PL) (by twofold) and triacylglycerol (TAG) fractions (by 2.3-fold, day 4). DPA supplementation also significantly increased the proportions of EPA in TAG (by 3.1-fold, day 4) and cholesterol ester (CE) fractions (by 2.0-fold, day 7) and of DHA in TAG fraction (by 3.1-fold, day 4). DPA proportions in RBC PL did not change following supplementation. Supplementation with EPA significantly increased the proportion of EPA in the plasma CE and PL fractions, (both by 2.7-fold, day 4 and day 7) and in the RBC PL (by 1.9-fold, day 4 and day 7). EPA supplementation did not alter the proportions of DPA or DHA in any lipid fraction. These results showed that within day 4 of supplementation, DPA and EPA demonstrated different and specific incorporation patterns.
Conclusion
The results of this short-term study suggest that DPA may act as a reservoir of the major long-chain n-3 fatty acids (LC n-3 PUFA) in humans. |
| doi_str_mv | 10.1007/s00394-012-0396-3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1322594591</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2933725341</sourcerecordid><originalsourceid>FETCH-LOGICAL-c481t-5258d951fc7b9fdc7aab68d9bdd870ec304f54d046a9f0b881d12dc9d44d77703</originalsourceid><addsrcrecordid>eNp1kEtPwzAQhC0EoqXwA7igSJwN61ccH6vylCrBAc6WEzu0VfPAdg7997hKqbhw2tXszKz0IXRN4I4AyPsAwBTHQChOS47ZCZoSznKcUyJOjzvICboIYQMAlOXkHE0olVSpXE4Rn2dh1fmIo_NN1mKWPbwnaej7rWtcG01cd20W4mB32brNVkNj2nCJzmqzDe7qMGfo8-nxY_GCl2_Pr4v5Ele8IBELKgqrBKkrWaraVtKYMk9KaW0hwVUMeC24BZ4bVUNZFMQSaitlObdSSmAzdDv29r77HlyIetMNvk0vNWGUCsWFIslFRlfluxC8q3Xv143xO01A7znpkZNOnPSek2Ypc3NoHsrG2WPiF0wy0NEQ0qn9cv7P639bfwCr4HEN</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1322594591</pqid></control><display><type>article</type><title>A short-term n-3 DPA supplementation study in humans</title><source>MEDLINE</source><source>SpringerLink Journals (MCLS)</source><creator>Miller, Eliza ; Kaur, Gunveen ; Larsen, Amy ; Loh, Su Peng ; Linderborg, Kaisa ; Weisinger, Harrison S. ; Turchini, Giovanni M. ; Cameron-Smith, David ; Sinclair, Andrew J.</creator><creatorcontrib>Miller, Eliza ; Kaur, Gunveen ; Larsen, Amy ; Loh, Su Peng ; Linderborg, Kaisa ; Weisinger, Harrison S. ; Turchini, Giovanni M. ; Cameron-Smith, David ; Sinclair, Andrew J.</creatorcontrib><description>Purpose
Despite the detailed knowledge of the absorption and incorporation of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) into plasma lipids and red blood cells (RBC) in humans, very little is known about docosapentaenoic acid (DPA, 22:5 n-3). The aim of this study was to investigate the uptake and incorporation of pure DPA and EPA into human plasma and RBC lipids.
Methods
Ten female participants received 8 g of pure DPA or pure EPA in randomized crossover double-blinded manner over a 7-day period. The placebo treatment was olive oil. Blood samples were collected at days zero, four and seven, following which the plasma and RBC were separated and used for the analysis of fatty acids.
Results
Supplementation with DPA significantly increased the proportions of DPA in the plasma phospholipids (PL) (by twofold) and triacylglycerol (TAG) fractions (by 2.3-fold, day 4). DPA supplementation also significantly increased the proportions of EPA in TAG (by 3.1-fold, day 4) and cholesterol ester (CE) fractions (by 2.0-fold, day 7) and of DHA in TAG fraction (by 3.1-fold, day 4). DPA proportions in RBC PL did not change following supplementation. Supplementation with EPA significantly increased the proportion of EPA in the plasma CE and PL fractions, (both by 2.7-fold, day 4 and day 7) and in the RBC PL (by 1.9-fold, day 4 and day 7). EPA supplementation did not alter the proportions of DPA or DHA in any lipid fraction. These results showed that within day 4 of supplementation, DPA and EPA demonstrated different and specific incorporation patterns.
Conclusion
The results of this short-term study suggest that DPA may act as a reservoir of the major long-chain n-3 fatty acids (LC n-3 PUFA) in humans.</description><identifier>ISSN: 1436-6207</identifier><identifier>EISSN: 1436-6215</identifier><identifier>DOI: 10.1007/s00394-012-0396-3</identifier><identifier>PMID: 22729967</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Adult ; Chemistry ; Chemistry and Materials Science ; Cholesterol Esters - blood ; Cholesterol Esters - chemistry ; Cholesterol Esters - metabolism ; Cross-Over Studies ; Diarrhea - etiology ; Dietary Supplements ; Docosahexaenoic Acids - adverse effects ; Docosahexaenoic Acids - analysis ; Docosahexaenoic Acids - blood ; Docosahexaenoic Acids - metabolism ; Double-Blind Method ; Eicosapentaenoic Acid - adverse effects ; Eicosapentaenoic Acid - analysis ; Eicosapentaenoic Acid - blood ; Eicosapentaenoic Acid - metabolism ; Erythrocytes - metabolism ; Fatty Acids, Unsaturated - adverse effects ; Fatty Acids, Unsaturated - analysis ; Fatty Acids, Unsaturated - blood ; Fatty Acids, Unsaturated - metabolism ; Female ; Food Preferences ; Humans ; Nutrition ; Original Contribution ; Phospholipids - blood ; Phospholipids - chemistry ; Phospholipids - metabolism ; Triglycerides - blood ; Triglycerides - chemistry ; Triglycerides - metabolism ; Victoria ; Young Adult</subject><ispartof>European journal of nutrition, 2013-04, Vol.52 (3), p.895-904</ispartof><rights>Springer-Verlag 2012</rights><rights>Springer-Verlag Berlin Heidelberg 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-5258d951fc7b9fdc7aab68d9bdd870ec304f54d046a9f0b881d12dc9d44d77703</citedby><cites>FETCH-LOGICAL-c481t-5258d951fc7b9fdc7aab68d9bdd870ec304f54d046a9f0b881d12dc9d44d77703</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00394-012-0396-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00394-012-0396-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22729967$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Miller, Eliza</creatorcontrib><creatorcontrib>Kaur, Gunveen</creatorcontrib><creatorcontrib>Larsen, Amy</creatorcontrib><creatorcontrib>Loh, Su Peng</creatorcontrib><creatorcontrib>Linderborg, Kaisa</creatorcontrib><creatorcontrib>Weisinger, Harrison S.</creatorcontrib><creatorcontrib>Turchini, Giovanni M.</creatorcontrib><creatorcontrib>Cameron-Smith, David</creatorcontrib><creatorcontrib>Sinclair, Andrew J.</creatorcontrib><title>A short-term n-3 DPA supplementation study in humans</title><title>European journal of nutrition</title><addtitle>Eur J Nutr</addtitle><addtitle>Eur J Nutr</addtitle><description>Purpose
Despite the detailed knowledge of the absorption and incorporation of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) into plasma lipids and red blood cells (RBC) in humans, very little is known about docosapentaenoic acid (DPA, 22:5 n-3). The aim of this study was to investigate the uptake and incorporation of pure DPA and EPA into human plasma and RBC lipids.
Methods
Ten female participants received 8 g of pure DPA or pure EPA in randomized crossover double-blinded manner over a 7-day period. The placebo treatment was olive oil. Blood samples were collected at days zero, four and seven, following which the plasma and RBC were separated and used for the analysis of fatty acids.
Results
Supplementation with DPA significantly increased the proportions of DPA in the plasma phospholipids (PL) (by twofold) and triacylglycerol (TAG) fractions (by 2.3-fold, day 4). DPA supplementation also significantly increased the proportions of EPA in TAG (by 3.1-fold, day 4) and cholesterol ester (CE) fractions (by 2.0-fold, day 7) and of DHA in TAG fraction (by 3.1-fold, day 4). DPA proportions in RBC PL did not change following supplementation. Supplementation with EPA significantly increased the proportion of EPA in the plasma CE and PL fractions, (both by 2.7-fold, day 4 and day 7) and in the RBC PL (by 1.9-fold, day 4 and day 7). EPA supplementation did not alter the proportions of DPA or DHA in any lipid fraction. These results showed that within day 4 of supplementation, DPA and EPA demonstrated different and specific incorporation patterns.
Conclusion
The results of this short-term study suggest that DPA may act as a reservoir of the major long-chain n-3 fatty acids (LC n-3 PUFA) in humans.</description><subject>Adult</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Cholesterol Esters - blood</subject><subject>Cholesterol Esters - chemistry</subject><subject>Cholesterol Esters - metabolism</subject><subject>Cross-Over Studies</subject><subject>Diarrhea - etiology</subject><subject>Dietary Supplements</subject><subject>Docosahexaenoic Acids - adverse effects</subject><subject>Docosahexaenoic Acids - analysis</subject><subject>Docosahexaenoic Acids - blood</subject><subject>Docosahexaenoic Acids - metabolism</subject><subject>Double-Blind Method</subject><subject>Eicosapentaenoic Acid - adverse effects</subject><subject>Eicosapentaenoic Acid - analysis</subject><subject>Eicosapentaenoic Acid - blood</subject><subject>Eicosapentaenoic Acid - metabolism</subject><subject>Erythrocytes - metabolism</subject><subject>Fatty Acids, Unsaturated - adverse effects</subject><subject>Fatty Acids, Unsaturated - analysis</subject><subject>Fatty Acids, Unsaturated - blood</subject><subject>Fatty Acids, Unsaturated - metabolism</subject><subject>Female</subject><subject>Food Preferences</subject><subject>Humans</subject><subject>Nutrition</subject><subject>Original Contribution</subject><subject>Phospholipids - blood</subject><subject>Phospholipids - chemistry</subject><subject>Phospholipids - metabolism</subject><subject>Triglycerides - blood</subject><subject>Triglycerides - chemistry</subject><subject>Triglycerides - metabolism</subject><subject>Victoria</subject><subject>Young Adult</subject><issn>1436-6207</issn><issn>1436-6215</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kEtPwzAQhC0EoqXwA7igSJwN61ccH6vylCrBAc6WEzu0VfPAdg7997hKqbhw2tXszKz0IXRN4I4AyPsAwBTHQChOS47ZCZoSznKcUyJOjzvICboIYQMAlOXkHE0olVSpXE4Rn2dh1fmIo_NN1mKWPbwnaej7rWtcG01cd20W4mB32brNVkNj2nCJzmqzDe7qMGfo8-nxY_GCl2_Pr4v5Ele8IBELKgqrBKkrWaraVtKYMk9KaW0hwVUMeC24BZ4bVUNZFMQSaitlObdSSmAzdDv29r77HlyIetMNvk0vNWGUCsWFIslFRlfluxC8q3Xv143xO01A7znpkZNOnPSek2Ypc3NoHsrG2WPiF0wy0NEQ0qn9cv7P639bfwCr4HEN</recordid><startdate>20130401</startdate><enddate>20130401</enddate><creator>Miller, Eliza</creator><creator>Kaur, Gunveen</creator><creator>Larsen, Amy</creator><creator>Loh, Su Peng</creator><creator>Linderborg, Kaisa</creator><creator>Weisinger, Harrison S.</creator><creator>Turchini, Giovanni M.</creator><creator>Cameron-Smith, David</creator><creator>Sinclair, Andrew J.</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RQ</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>20130401</creationdate><title>A short-term n-3 DPA supplementation study in humans</title><author>Miller, Eliza ; Kaur, Gunveen ; Larsen, Amy ; Loh, Su Peng ; Linderborg, Kaisa ; Weisinger, Harrison S. ; Turchini, Giovanni M. ; Cameron-Smith, David ; Sinclair, Andrew J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-5258d951fc7b9fdc7aab68d9bdd870ec304f54d046a9f0b881d12dc9d44d77703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Cholesterol Esters - blood</topic><topic>Cholesterol Esters - chemistry</topic><topic>Cholesterol Esters - metabolism</topic><topic>Cross-Over Studies</topic><topic>Diarrhea - etiology</topic><topic>Dietary Supplements</topic><topic>Docosahexaenoic Acids - adverse effects</topic><topic>Docosahexaenoic Acids - analysis</topic><topic>Docosahexaenoic Acids - blood</topic><topic>Docosahexaenoic Acids - metabolism</topic><topic>Double-Blind Method</topic><topic>Eicosapentaenoic Acid - adverse effects</topic><topic>Eicosapentaenoic Acid - analysis</topic><topic>Eicosapentaenoic Acid - blood</topic><topic>Eicosapentaenoic Acid - metabolism</topic><topic>Erythrocytes - metabolism</topic><topic>Fatty Acids, Unsaturated - adverse effects</topic><topic>Fatty Acids, Unsaturated - analysis</topic><topic>Fatty Acids, Unsaturated - blood</topic><topic>Fatty Acids, Unsaturated - metabolism</topic><topic>Female</topic><topic>Food Preferences</topic><topic>Humans</topic><topic>Nutrition</topic><topic>Original Contribution</topic><topic>Phospholipids - blood</topic><topic>Phospholipids - chemistry</topic><topic>Phospholipids - metabolism</topic><topic>Triglycerides - blood</topic><topic>Triglycerides - chemistry</topic><topic>Triglycerides - metabolism</topic><topic>Victoria</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Miller, Eliza</creatorcontrib><creatorcontrib>Kaur, Gunveen</creatorcontrib><creatorcontrib>Larsen, Amy</creatorcontrib><creatorcontrib>Loh, Su Peng</creatorcontrib><creatorcontrib>Linderborg, Kaisa</creatorcontrib><creatorcontrib>Weisinger, Harrison S.</creatorcontrib><creatorcontrib>Turchini, Giovanni M.</creatorcontrib><creatorcontrib>Cameron-Smith, David</creatorcontrib><creatorcontrib>Sinclair, Andrew J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Career & Technical Education Database</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>European journal of nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Miller, Eliza</au><au>Kaur, Gunveen</au><au>Larsen, Amy</au><au>Loh, Su Peng</au><au>Linderborg, Kaisa</au><au>Weisinger, Harrison S.</au><au>Turchini, Giovanni M.</au><au>Cameron-Smith, David</au><au>Sinclair, Andrew J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A short-term n-3 DPA supplementation study in humans</atitle><jtitle>European journal of nutrition</jtitle><stitle>Eur J Nutr</stitle><addtitle>Eur J Nutr</addtitle><date>2013-04-01</date><risdate>2013</risdate><volume>52</volume><issue>3</issue><spage>895</spage><epage>904</epage><pages>895-904</pages><issn>1436-6207</issn><eissn>1436-6215</eissn><abstract>Purpose
Despite the detailed knowledge of the absorption and incorporation of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) into plasma lipids and red blood cells (RBC) in humans, very little is known about docosapentaenoic acid (DPA, 22:5 n-3). The aim of this study was to investigate the uptake and incorporation of pure DPA and EPA into human plasma and RBC lipids.
Methods
Ten female participants received 8 g of pure DPA or pure EPA in randomized crossover double-blinded manner over a 7-day period. The placebo treatment was olive oil. Blood samples were collected at days zero, four and seven, following which the plasma and RBC were separated and used for the analysis of fatty acids.
Results
Supplementation with DPA significantly increased the proportions of DPA in the plasma phospholipids (PL) (by twofold) and triacylglycerol (TAG) fractions (by 2.3-fold, day 4). DPA supplementation also significantly increased the proportions of EPA in TAG (by 3.1-fold, day 4) and cholesterol ester (CE) fractions (by 2.0-fold, day 7) and of DHA in TAG fraction (by 3.1-fold, day 4). DPA proportions in RBC PL did not change following supplementation. Supplementation with EPA significantly increased the proportion of EPA in the plasma CE and PL fractions, (both by 2.7-fold, day 4 and day 7) and in the RBC PL (by 1.9-fold, day 4 and day 7). EPA supplementation did not alter the proportions of DPA or DHA in any lipid fraction. These results showed that within day 4 of supplementation, DPA and EPA demonstrated different and specific incorporation patterns.
Conclusion
The results of this short-term study suggest that DPA may act as a reservoir of the major long-chain n-3 fatty acids (LC n-3 PUFA) in humans.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>22729967</pmid><doi>10.1007/s00394-012-0396-3</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1436-6207 |
| ispartof | European journal of nutrition, 2013-04, Vol.52 (3), p.895-904 |
| issn | 1436-6207 1436-6215 |
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| subjects | Adult Chemistry Chemistry and Materials Science Cholesterol Esters - blood Cholesterol Esters - chemistry Cholesterol Esters - metabolism Cross-Over Studies Diarrhea - etiology Dietary Supplements Docosahexaenoic Acids - adverse effects Docosahexaenoic Acids - analysis Docosahexaenoic Acids - blood Docosahexaenoic Acids - metabolism Double-Blind Method Eicosapentaenoic Acid - adverse effects Eicosapentaenoic Acid - analysis Eicosapentaenoic Acid - blood Eicosapentaenoic Acid - metabolism Erythrocytes - metabolism Fatty Acids, Unsaturated - adverse effects Fatty Acids, Unsaturated - analysis Fatty Acids, Unsaturated - blood Fatty Acids, Unsaturated - metabolism Female Food Preferences Humans Nutrition Original Contribution Phospholipids - blood Phospholipids - chemistry Phospholipids - metabolism Triglycerides - blood Triglycerides - chemistry Triglycerides - metabolism Victoria Young Adult |
| title | A short-term n-3 DPA supplementation study in humans |
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