All-oral combination of vinorelbine and capecitabine as first-line treatment in HER2/Neu-negative metastatic breast cancer

Purpose To evaluate the efficacy and safety of an all-oral vinorelbine and capecitabine combination therapy in anthracycline- ± taxane-pretreated HER2/Neu-negative metastatic breast cancer (MBC). Methods A phase 2 trial including women >18 years with HER2/Neu-negative MBC previously exposed to an...

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Veröffentlicht in:	Cancer chemotherapy and pharmacology 2013-04, Vol.71 (4), p.913-919
Hauptverfasser:	Tawfik, Hesham, Rostom, Yousri, Elghazaly, Hesham
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Aged Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Breast Neoplasms - chemistry Breast Neoplasms - drug therapy Breast Neoplasms - mortality Breast Neoplasms - pathology Cancer Research Capecitabine Deoxycytidine - administration & dosage Deoxycytidine - adverse effects Deoxycytidine - analogs & derivatives Female Fluorouracil - administration & dosage Fluorouracil - adverse effects Fluorouracil - analogs & derivatives General aspects Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Medicine Medicine & Public Health Middle Aged Neoplasm Metastasis Oncology Original Article Pharmacology. Drug treatments Pharmacology/Toxicology Receptor, ErbB-2 - analysis Tumors Vinblastine - administration & dosage Vinblastine - adverse effects Vinblastine - analogs & derivatives
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