11C Click Chemistry Using [11C]Methyl Azide: Simplified, Versatile, and Practical Alternative Access to [11C]Nucleosides and [11C]Oligonucleotides for PET Imaging

This communication reports the simplified formation of methyl azide and its use in the Huisgen cycloaddition for the rapid, efficient, and selective labeling of modified nucleosides and oligonucleotides. The transposition to radioactive chemistry is presented, and this furnishes practical access to...

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Veröffentlicht in:	European journal of organic chemistry 2013-03, Vol.2013 (7), p.1214-1217
Hauptverfasser:	Bordenave, Thomas, Hazari, Puja Panwar, James, Damien, Mishra, Anil K., Szlosek-Pinaud, Magali, Fouquet, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Click chemistry Isotopic labeling Medical imaging Nucleosides Positron emission tomography Radiochemistry Tomography
Online-Zugang:	Volltext
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