RNA interference and deep sequencing as tools for identifying new genes involved in leukemogenesis

The establishment of the molecular mechanisms of occurrence and progression of oncological diseases and the development of effective tools to combat them is an important field of modern biomedicine. Today, the complete set of genes involved in carcinogenesis is not known for the majority of types of...

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Veröffentlicht in:	Doklady. Biochemistry and biophysics 2013, Vol.448 (1), p.49-51
Hauptverfasser:	Lebedev, T. D., Spirin, P. V., Orlova, N. N., Kudryavtseva, A. V., Melnikova, N. V., Speranskaya, A. S., Prasolov, V. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biomedical research Biophysics Biophysics and Molecular Biology Cell Line, Tumor Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - metabolism Core Binding Factor Alpha 2 Subunit - genetics Core Binding Factor Alpha 2 Subunit - metabolism DNA Mutational Analysis - methods Genes, Neoplasm Humans Leukemia Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - metabolism Leukemia, Myeloid, Acute - pathology Life Sciences Molecular biology Oncogene Proteins, Fusion - genetics Oncogene Proteins, Fusion - metabolism Proto-Oncogene Proteins c-kit - genetics Proto-Oncogene Proteins c-kit - metabolism Ribonucleic acid RNA RNA Interference RUNX1 Translocation Partner 1 Protein
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