Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics: e1000021

Macrophages are versatile immune cells that can detect a variety of pathogen-associated molecular patterns through their Toll-like receptors (TLRs). In response to microbial challenge, the TLR-stimulated macrophage undergoes an activation program controlled by a dynamically inducible transcriptional...

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Veröffentlicht in:	PLoS computational biology 2008-03, Vol.4 (3)
Hauptverfasser:	Ramsey, Stephen A, Klemm, Sandy L, Zak, Daniel E, Kennedy, Kathleen A, Thorsson, Vesteinn, Li, Bin, Gilchrist, Mark, Gold, Elizabeth S, Johnson, Carrie D, Litvak, Vladimir, Navarro, Garnet, Roach, Jared C, Rosenberger, Carrie M, Rust, Alistair G, Yudkovsky, Natalya, Aderem, Alan, Shmulevich, Ilya
Format:	Artikel
Sprache:	eng
Schlagworte:	Data processing Experiments Genes Immune system Infections Methods Proteins
Online-Zugang:	Volltext
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