Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD: e1001053

Recently, genetic association findings for nicotine dependence, smoking behavior, and smoking-related diseases converged to implicate the chromosome 15q25.1 region, which includes the CHRNA5-CHRNA3-CHRNB4 cholinergic nicotinic receptor subunit genes. In particular, association with the nonsynonymous...

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Veröffentlicht in:	PLoS genetics 2010-08, Vol.6 (8)
Hauptverfasser:	Saccone, Nancy L, Culverhouse, Robert C, Schwantes-An, Tae-Hwi, Cannon, Dale S, Chen, Xiangning, Cichon, Sven, Giegling, Ina, Han, Shizhong, Han, Younghun, Keskitalo-Vuokko, Kaisu, Kong, Xiangyang, Landi, Maria Teresa, Ma, Jennie Z, Short, Susan E, Stephens, Sarah H, Stevens, Victoria L, Sun, Lingwei, Wang, Yufei, Wenzlaff, Angela S, Aggen, Steven H, Breslau, Naomi, Broderick, Peter, Chatterjee, Nilanjan, Chen, Jingchun, Heath, Andrew C, Heliövaara, Markku, Hoft, Nicole R, Hunter, David J, Jensen, Majken K, Martin, Nicholas G, Montgomery, Grant W, Niu, Tianhua, Payne, Thomas J, Peltonen, Leena, Pergadia, Michele L, Rice, John P, Sherva, Richard, Spitz, Margaret R, Sun, Juzhong, Wang, Jen C, Weiss, Robert B, Wheeler, William, Witt, Stephanie H, Yang, Bao-Zhu, Caporaso, Neil E, Ehringer, Marissa A, Eisen, Tim, Gapstur, Susan M, Gelernter, Joel, Houlston, Richard, Kaprio, Jaakko, Kendler, Kenneth S, Kraft, Peter, Leppert, Mark F, Li, Ming D, Madden, Pamela AF, Nöthen, Markus M, Pillai, Sreekumar, Rietschel, Marcella, Rujescu, Dan, Schwartz, Ann, Amos, Christopher I, Bierut, Laura J
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic obstructive pulmonary disease Genetics Lung cancer Nicotine Smoking
Online-Zugang:	Volltext
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