On the safety of long-term treatment with lithium
Thirteen patients with bipolar affective illness who had received lithium therapy for 1-5 years were tested retrospectively for evidence of cortical dysfunction. Data on patients younger than 55 show no abnormalities on the Halstead-Reitan Neuropsychological Battery and suggest that chronic lithium...
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Veröffentlicht in: | The American journal of psychiatry 1977-10, Vol.134 (10), p.1123-1126 |
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container_title | The American journal of psychiatry |
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creator | Friedman, M J Culver, C M Ferrell, R B |
description | Thirteen patients with bipolar affective illness who had received
lithium therapy for 1-5 years were tested retrospectively for evidence of
cortical dysfunction. Data on patients younger than 55 show no
abnormalities on the Halstead-Reitan Neuropsychological Battery and suggest
that chronic lithium therapy is relatively safe. Significantly elevated
Halstead Impairment indexes were observed among elderly patients, but these
data are difficult to interpret. |
doi_str_mv | 10.1176/ajp.134.10.1123 |
format | Article |
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lithium therapy for 1-5 years were tested retrospectively for evidence of
cortical dysfunction. Data on patients younger than 55 show no
abnormalities on the Halstead-Reitan Neuropsychological Battery and suggest
that chronic lithium therapy is relatively safe. Significantly elevated
Halstead Impairment indexes were observed among elderly patients, but these
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lithium therapy for 1-5 years were tested retrospectively for evidence of
cortical dysfunction. Data on patients younger than 55 show no
abnormalities on the Halstead-Reitan Neuropsychological Battery and suggest
that chronic lithium therapy is relatively safe. Significantly elevated
Halstead Impairment indexes were observed among elderly patients, but these
data are difficult to interpret.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Bipolar Disorder - drug therapy</subject><subject>Cognition Disorders - chemically induced</subject><subject>Cortical Synchronization</subject><subject>Female</subject><subject>Humans</subject><subject>Lithium - administration & dosage</subject><subject>Lithium - adverse effects</subject><subject>Lithium - blood</subject><subject>Long-Term Care</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Psychological Tests</subject><issn>0002-953X</issn><issn>1535-7228</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>K30</sourceid><recordid>eNp1UE1LAzEUDOJXrZ69eAh4dduXZJNsjlL8gkIvCt6W7G5it3Q_TLJI_72pW8SLl_cYZt4MbxC6JjAjRIq53vQzwtLZD6bsCE0IZzyRlGbHaAIANFGcvZ-jC-83EQKT9AydpqAYwASRVYvD2mCvrQk73Fm87dqPJBjX4OCMDo1pA_6qwxpv46iH5hKdWL315uqwp-jt8eF18ZwsV08vi_tlohkXISl5mglrUyWM0hJUYStCC5pZVUpZmUxonlXcGi5FKgoqBVfAbGkk2zNg2RTdjr696z4H40O-6QbXxsicMAICWBb_naL5qCpd570zNu9d3Wi3ywnk-4LyWFA8SEdMWby4OfgORWOqX_3YSKTvRlr3ff0n8h-3b6fRbVQ</recordid><startdate>197710</startdate><enddate>197710</enddate><creator>Friedman, M J</creator><creator>Culver, C M</creator><creator>Ferrell, R B</creator><general>American Psychiatric Publishing</general><general>American Psychiatric Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>HAWNG</scope><scope>HBMBR</scope><scope>IBDFT</scope><scope>K30</scope><scope>PAAUG</scope><scope>PAWHS</scope><scope>PAWZZ</scope><scope>PAXOH</scope><scope>PBHAV</scope><scope>PBQSW</scope><scope>PBYQZ</scope><scope>PCIWU</scope><scope>PCMID</scope><scope>PCZJX</scope><scope>PDGRG</scope><scope>PDWWI</scope><scope>PETMR</scope><scope>PFVGT</scope><scope>PGXDX</scope><scope>PIHIL</scope><scope>PISVA</scope><scope>PJCTQ</scope><scope>PJTMS</scope><scope>PLCHJ</scope><scope>PMHAD</scope><scope>PNQDJ</scope><scope>POUND</scope><scope>PPLAD</scope><scope>PQAPC</scope><scope>PQCAN</scope><scope>PQCMW</scope><scope>PQEME</scope><scope>PQHKH</scope><scope>PQMID</scope><scope>PQNCT</scope><scope>PQNET</scope><scope>PQSCT</scope><scope>PQSET</scope><scope>PSVJG</scope><scope>PVMQY</scope><scope>PZGFC</scope></search><sort><creationdate>197710</creationdate><title>On the safety of long-term treatment with lithium</title><author>Friedman, M J ; 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lithium therapy for 1-5 years were tested retrospectively for evidence of
cortical dysfunction. Data on patients younger than 55 show no
abnormalities on the Halstead-Reitan Neuropsychological Battery and suggest
that chronic lithium therapy is relatively safe. Significantly elevated
Halstead Impairment indexes were observed among elderly patients, but these
data are difficult to interpret.</abstract><cop>United States</cop><pub>American Psychiatric Publishing</pub><pmid>409300</pmid><doi>10.1176/ajp.134.10.1123</doi><tpages>4</tpages></addata></record> |
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language | eng |
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source | MEDLINE; Psychiatry Legacy Collection Online Journals 1844-1996; Periodicals Index Online |
subjects | Adolescent Adult Age Factors Aged Bipolar Disorder - drug therapy Cognition Disorders - chemically induced Cortical Synchronization Female Humans Lithium - administration & dosage Lithium - adverse effects Lithium - blood Long-Term Care Male Middle Aged Psychological Tests |
title | On the safety of long-term treatment with lithium |
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