On the safety of long-term treatment with lithium

Thirteen patients with bipolar affective illness who had received lithium therapy for 1-5 years were tested retrospectively for evidence of cortical dysfunction. Data on patients younger than 55 show no abnormalities on the Halstead-Reitan Neuropsychological Battery and suggest that chronic lithium...

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Veröffentlicht in:The American journal of psychiatry 1977-10, Vol.134 (10), p.1123-1126
Hauptverfasser: Friedman, M J, Culver, C M, Ferrell, R B
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container_issue 10
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container_title The American journal of psychiatry
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creator Friedman, M J
Culver, C M
Ferrell, R B
description Thirteen patients with bipolar affective illness who had received lithium therapy for 1-5 years were tested retrospectively for evidence of cortical dysfunction. Data on patients younger than 55 show no abnormalities on the Halstead-Reitan Neuropsychological Battery and suggest that chronic lithium therapy is relatively safe. Significantly elevated Halstead Impairment indexes were observed among elderly patients, but these data are difficult to interpret.
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source MEDLINE; Psychiatry Legacy Collection Online Journals 1844-1996; Periodicals Index Online
subjects Adolescent
Adult
Age Factors
Aged
Bipolar Disorder - drug therapy
Cognition Disorders - chemically induced
Cortical Synchronization
Female
Humans
Lithium - administration & dosage
Lithium - adverse effects
Lithium - blood
Long-Term Care
Male
Middle Aged
Psychological Tests
title On the safety of long-term treatment with lithium
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