ORAL CONTRACEPTIVES, SMOKING, AND OTHER FACTORS IN RELATION TO RISK OF VENOUS THROMBOEMBOLIC DISEASE

Analysis of data from the Walnut Creek Contraceptive Drug Study showed a significant increase in risk of venous thromboembolic disease In the absence of surgery, trauma, malignancy, pregnancy, and the puerperium for women with a previous history of thromboembolism, hypertension, diabetes, varicose v...

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Veröffentlicht in:American journal of epidemiology 1978-12, Vol.108 (6), p.480-485
Hauptverfasser: PETITTI, DIANA B., WINGERD, JOHN, PELLEGRIN, FREDERICK, RAMCHARAN, SAVITRI
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container_end_page 485
container_issue 6
container_start_page 480
container_title American journal of epidemiology
container_volume 108
creator PETITTI, DIANA B.
WINGERD, JOHN
PELLEGRIN, FREDERICK
RAMCHARAN, SAVITRI
description Analysis of data from the Walnut Creek Contraceptive Drug Study showed a significant increase in risk of venous thromboembolic disease In the absence of surgery, trauma, malignancy, pregnancy, and the puerperium for women with a previous history of thromboembolism, hypertension, diabetes, varicose veins, gallbladder disease, and cigarette smoking. Education, marital status, parity, use of noncontraceptive estrogens, and obesity were not associated with an Increase in risk of the disease. When only cases of the disease in the absence of all known predisposing causes (idiopathic cases) were analyzed, both oral contraceptive use and smoking remained as independent risk factors; there was no evidence of a positive interaction between them.
doi_str_mv 10.1093/oxfordjournals.aje.a112646
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ispartof American journal of epidemiology, 1978-12, Vol.108 (6), p.480-485
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source Oxford University Press Journals Digital Archive legacy; MEDLINE; Periodicals Index Online
subjects Adult
Contraceptives, Oral - adverse effects
estrogens
Female
Humans
hypertension
Middle Aged
oral contraceptives
Risk
smoking
Smoking - complications
thromboembolism
Thromboembolism - chemically induced
Thromboembolism - diagnosis
Thromboembolism - etiology
title ORAL CONTRACEPTIVES, SMOKING, AND OTHER FACTORS IN RELATION TO RISK OF VENOUS THROMBOEMBOLIC DISEASE
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