EPIDEMIOLOGIC INVESTIGATION OF AN OIL-ASSOCIATED PNEUMONIC PARALYTIC EOSINOPHILIC SYNDROME IN SPAIN
Rlgau-Pérez, J. G. (Epidemiology Program Office, CDC, Atlanta, GA 30333), L. Pérez-Alvarez, S. Duenas-Castro, K. Choi, S. B. Thacker, J. L. Germain, G. González-de-Andrés, L. Canada-Royo and F. Pérez-Gallardo. Epidemiologic investigation of an oll-assoclated pneumonic paralytic eoslnophlllc syndrome...
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| Veröffentlicht in: | American journal of epidemiology 1984-02, Vol.119 (2), p.250-260 |
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| creator | RIGAU-PÉREZ, JOSÉ G. PÉREZ-ALVAREZ, LUIS DUENAS-CASTRO, SEGUNDO CHOI, KEEWHAN THACKER, STEPHEN B. GERMAIN, JOSÉL. GONZÁLEZ-DE-ANDRÉS, GERMÁN CANADA-ROYO, LUIS PÉREZ-GALLARDO, FLORENCIO |
| description | Rlgau-Pérez, J. G. (Epidemiology Program Office, CDC, Atlanta, GA 30333), L. Pérez-Alvarez, S. Duenas-Castro, K. Choi, S. B. Thacker, J. L. Germain, G. González-de-Andrés, L. Canada-Royo and F. Pérez-Gallardo. Epidemiologic investigation of an oll-assoclated pneumonic paralytic eoslnophlllc syndrome in Spain. Am J Epidemiol 1984; 119: 250–60. From May 1 to December 26, 1961, a previously undescribed illness caused 277 deaths and the hospitalizatlon of 12, 656 persons in Spain. The disease was characterized by pneumonltls, eoslnophllia, and marked loss of muscle mass and function. A succession of case-control studies was done in the town of Las Navas del Marqués (province of Avila) located 47 miles northeast of Madrid and with a population of 4009 people. The studies confirmed the association between illness and consumption of an illegally sold cooking oil. Other risk factors identified in the linear logistic regression analysis included involvement in various kitchen activities, increased average time spent inside the house, and the purchase of cooking oil from a specific street vendor. Although the oil was found to be a mixture of vegetable and animal fats contaminated with aniline and anillde-oll complexes, the specific etlologlc mechanism of the disease has not been determined. |
| doi_str_mv | 10.1093/oxfordjournals.aje.a113744 |
| format | Article |
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G. (Epidemiology Program Office, CDC, Atlanta, GA 30333), L. Pérez-Alvarez, S. Duenas-Castro, K. Choi, S. B. Thacker, J. L. Germain, G. González-de-Andrés, L. Canada-Royo and F. Pérez-Gallardo. Epidemiologic investigation of an oll-assoclated pneumonic paralytic eoslnophlllc syndrome in Spain. Am J Epidemiol 1984; 119: 250–60. From May 1 to December 26, 1961, a previously undescribed illness caused 277 deaths and the hospitalizatlon of 12, 656 persons in Spain. The disease was characterized by pneumonltls, eoslnophllia, and marked loss of muscle mass and function. A succession of case-control studies was done in the town of Las Navas del Marqués (province of Avila) located 47 miles northeast of Madrid and with a population of 4009 people. The studies confirmed the association between illness and consumption of an illegally sold cooking oil. Other risk factors identified in the linear logistic regression analysis included involvement in various kitchen activities, increased average time spent inside the house, and the purchase of cooking oil from a specific street vendor. Although the oil was found to be a mixture of vegetable and animal fats contaminated with aniline and anillde-oll complexes, the specific etlologlc mechanism of the disease has not been determined.</description><identifier>ISSN: 0002-9262</identifier><identifier>EISSN: 1476-6256</identifier><identifier>DOI: 10.1093/oxfordjournals.aje.a113744</identifier><identifier>PMID: 6695904</identifier><identifier>CODEN: AJEPAS</identifier><language>eng</language><publisher>Cary, NC: Oxford University Press</publisher><subject>Adolescent ; Adult ; Aged ; Biological and medical sciences ; Brassica ; Child ; Child, Preschool ; Disease Outbreaks - epidemiology ; eosinophllia ; Epidemiologic Methods ; Female ; Food Contamination ; Food toxicology ; Hospitalization ; Humans ; Infant ; Male ; Medical sciences ; Middle Aged ; Oils ; paralysis ; Paralysis - epidemiology ; Paralysis - etiology ; pneumonia ; Pulmonary Eosinophilia - epidemiology ; Pulmonary Eosinophilia - etiology ; Spain ; Syndrome ; Toxicology</subject><ispartof>American journal of epidemiology, 1984-02, Vol.119 (2), p.250-260</ispartof><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c461t-b89cf040202a9de78862ff9d11fc1fb861763b15640392937162ce2817e846473</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27869,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9666462$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6695904$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>RIGAU-PÉREZ, JOSÉ G.</creatorcontrib><creatorcontrib>PÉREZ-ALVAREZ, LUIS</creatorcontrib><creatorcontrib>DUENAS-CASTRO, SEGUNDO</creatorcontrib><creatorcontrib>CHOI, KEEWHAN</creatorcontrib><creatorcontrib>THACKER, STEPHEN B.</creatorcontrib><creatorcontrib>GERMAIN, JOSÉL.</creatorcontrib><creatorcontrib>GONZÁLEZ-DE-ANDRÉS, GERMÁN</creatorcontrib><creatorcontrib>CANADA-ROYO, LUIS</creatorcontrib><creatorcontrib>PÉREZ-GALLARDO, FLORENCIO</creatorcontrib><title>EPIDEMIOLOGIC INVESTIGATION OF AN OIL-ASSOCIATED PNEUMONIC PARALYTIC EOSINOPHILIC SYNDROME IN SPAIN</title><title>American journal of epidemiology</title><addtitle>Am J Epidemiol</addtitle><description>Rlgau-Pérez, J. G. (Epidemiology Program Office, CDC, Atlanta, GA 30333), L. Pérez-Alvarez, S. Duenas-Castro, K. Choi, S. B. Thacker, J. L. Germain, G. González-de-Andrés, L. Canada-Royo and F. Pérez-Gallardo. Epidemiologic investigation of an oll-assoclated pneumonic paralytic eoslnophlllc syndrome in Spain. Am J Epidemiol 1984; 119: 250–60. From May 1 to December 26, 1961, a previously undescribed illness caused 277 deaths and the hospitalizatlon of 12, 656 persons in Spain. The disease was characterized by pneumonltls, eoslnophllia, and marked loss of muscle mass and function. A succession of case-control studies was done in the town of Las Navas del Marqués (province of Avila) located 47 miles northeast of Madrid and with a population of 4009 people. The studies confirmed the association between illness and consumption of an illegally sold cooking oil. Other risk factors identified in the linear logistic regression analysis included involvement in various kitchen activities, increased average time spent inside the house, and the purchase of cooking oil from a specific street vendor. Although the oil was found to be a mixture of vegetable and animal fats contaminated with aniline and anillde-oll complexes, the specific etlologlc mechanism of the disease has not been determined.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Brassica</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Disease Outbreaks - epidemiology</subject><subject>eosinophllia</subject><subject>Epidemiologic Methods</subject><subject>Female</subject><subject>Food Contamination</subject><subject>Food toxicology</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Oils</subject><subject>paralysis</subject><subject>Paralysis - epidemiology</subject><subject>Paralysis - etiology</subject><subject>pneumonia</subject><subject>Pulmonary Eosinophilia - 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G. (Epidemiology Program Office, CDC, Atlanta, GA 30333), L. Pérez-Alvarez, S. Duenas-Castro, K. Choi, S. B. Thacker, J. L. Germain, G. González-de-Andrés, L. Canada-Royo and F. Pérez-Gallardo. Epidemiologic investigation of an oll-assoclated pneumonic paralytic eoslnophlllc syndrome in Spain. Am J Epidemiol 1984; 119: 250–60. From May 1 to December 26, 1961, a previously undescribed illness caused 277 deaths and the hospitalizatlon of 12, 656 persons in Spain. The disease was characterized by pneumonltls, eoslnophllia, and marked loss of muscle mass and function. A succession of case-control studies was done in the town of Las Navas del Marqués (province of Avila) located 47 miles northeast of Madrid and with a population of 4009 people. The studies confirmed the association between illness and consumption of an illegally sold cooking oil. 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| ispartof | American journal of epidemiology, 1984-02, Vol.119 (2), p.250-260 |
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| subjects | Adolescent Adult Aged Biological and medical sciences Brassica Child Child, Preschool Disease Outbreaks - epidemiology eosinophllia Epidemiologic Methods Female Food Contamination Food toxicology Hospitalization Humans Infant Male Medical sciences Middle Aged Oils paralysis Paralysis - epidemiology Paralysis - etiology pneumonia Pulmonary Eosinophilia - epidemiology Pulmonary Eosinophilia - etiology Spain Syndrome Toxicology |
| title | EPIDEMIOLOGIC INVESTIGATION OF AN OIL-ASSOCIATED PNEUMONIC PARALYTIC EOSINOPHILIC SYNDROME IN SPAIN |
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