CDC5 Inhibits the Hyperphosphorylation of the Checkpoint Kinase Rad53, Leading to Checkpoint Adaptation: e1000286

The Saccharomyces cerevisiae polo-like kinase Cdc5 promotes adaptation to the DNA damage checkpoint, in addition to its numerous roles in mitotic progression. The process of adaptation occurs when cells are presented with persistent or irreparable DNA damage and escape the cell-cycle arrest imposed...

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Veröffentlicht in:	PLoS biology 2010-01, Vol.8 (1)
Hauptverfasser:	Vidanes, Genevieve M, Sweeney, Frédéric D, Galicia, Sarah, Cheung, Stephanie, Doyle, John P, Durocher, Daniel, Toczyski, David P
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cyclin-dependent kinases DNA damage Genetics Genomes Phosphorylation Plasmids Sensors Sucrose
Online-Zugang:	Volltext
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