Mammalian Kinesin-3 Motors Are Dimeric In Vivo and Move by Processive Motility upon Release of Autoinhibition: e1000072

Kinesin-3 motors drive the transport of synaptic vesicles and other membrane-bound organelles in neuronal cells. In the absence of cargo, kinesin motors are kept inactive to prevent motility and ATP hydrolysis. Current models state that the Kinesin-3 motor KIF1A is monomeric in the inactive state an...

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Veröffentlicht in:	PLoS biology 2009-03, Vol.7 (3)
Hauptverfasser:	Hammond, Jennetta W, Cai, Dawen, Blasius, T Lynne, Li, Zhe, Jiang, Yuyang, Jih, Gloria T, Meyhofer, Edgar, Verhey, Kristen J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular biology Lasers Molecular weight Motility Proteins
Online-Zugang:	Volltext
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