The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-[kappa]B p65: e1000898

Many bacterial pathogens utilize a type III secretion system to deliver multiple effector proteins into host cells. Here we found that the type III effectors, NleE from enteropathogenic E. coli (EPEC) and OspZ from Shigella, blocked translocation of the p65 subunit of the transcription factor, NF-κB...

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Veröffentlicht in:	PLoS pathogens 2010-05, Vol.6 (5)
Hauptverfasser:	Newton, Hayley J, Pearson, Jaclyn S, Badea, Luminita, Kelly, Michelle, Lucas, Mark, Holloway, Gavan, Wagstaff, Kylie M, Dunstone, Michelle A, Sloan, Joan, Whisstock, James C, Kaper, James B, Robins-Browne, Roy M, Jans, David A, Frankel, Gad, Phillips, Alan D, Coulson, Barbara S, Hartland, Elizabeth L
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Binding sites E coli Gene expression Kinases Plasmids Proteins
Online-Zugang:	Volltext
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